Evidence map›Paper›PMID 37163088›Full record

ArticlebioRxiv : the preprint server for biology2023

The mitochondrial Ca

Emily Fernández García, Usha Paudel, Michael C Noji, Caitlyn E Bowman, Jason R Pitarresi, Anil K Rustgi, Kathryn E Wellen, Zolt Arany, Jillian S Weissenrieder, J Kevin Foskett

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Emily Fernández GarcíaDepartment of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Usha PaudelDepartment of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Michael C NojiDepartment of Cancer Biology and Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Caitlyn E BowmanCardiovascular Institute, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Jason R PitarresiDivision of Hematology/Oncology, Departments of Medicine and Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Anil K RustgiDivision of Digestive and Liver Diseases, Herbert Irving Comprehensive Cancer Center, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, USA.
Kathryn E WellenDepartment of Cancer Biology and Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Zolt AranyCardiovascular Institute, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Jillian S WeissenriederDepartment of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
J Kevin FoskettDepartment of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
University of Pennsylvania · USCancer Research Institute · USColumbia University Irving Medical Center · USUniversity of Massachusetts Chan Medical School · US

Funding

Tumor Biology and Microenvironment ProgramP30CA013696 · NCI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Parisa Tehranifar · 1985 to 2026
$115.3M
Training Program in Cardiovascular Biology and MedicineT32HL007843 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI THOMAS P. CAPPOLA, Sharlene M Day · 1996 to 2026
$11.0M
The Prrx-1 transcription factor in pancreatic ductal biologyR01DK060694 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI CHANDWANI, ROHIT, RUSTGI, ANIL K · 2002 to 2025
$8.3M
Electrophysiology of nuclear membrane InsP3 receptorR37GM056328 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI FOSKETT, JAMES KEVIN · 2011 to 2020
$4.9M
Branched chain amino acids in heart failureR01HL152446 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI Zoltan P Arany · 2020 to 2026
$3.7M
Branched chain amino acids in pancreatic carcinogenesisR01CA248315 · NCI · UNIVERSITY OF PENNSYLVANIA · PI Zoltan P Arany, Kathryn Elaine Wellen · 2020 to 2026
$2.8M
Endoplasmic Reticulum-to-Mitochondria Calcium Transfer in Pancreatic Cancer Development, Metastasis, and TreatmentR01CA250173 · NCI · UNIVERSITY OF PENNSYLVANIA · PI FOSKETT, JAMES KEVIN · 2021 to 2025
$2.6M
Dissecting the oncogenic and pro-metastatic roles of PTHLH-mediated calcium signaling in pancreatic cancerK99CA252153 · NCI · UNIVERSITY OF PENNSYLVANIA · PI PITARRESI, JASON R. · 2021 to 2022
$275k
The Mitochondrial Calcium Uniporter in Pancreatic Cancer Development, Metastasis, and TreatmentF32CA250144 · NCI · UNIVERSITY OF PENNSYLVANIA · PI WEISSENRIEDER, JILLIAN · 2021 to 2023
$205k
The role of branched-chain amino acid metabolism and hyperinsulinemia in pancreatic cancerF31CA261041 · NCI · UNIVERSITY OF PENNSYLVANIA · PI NOJI, MICHAEL · 2022 to 2024
$131k
NCI NIH HHS F31 CA261041NCI NIH HHS F32 CA250144NCI NIH HHS K99 CA252153NCI NIH HHS P30 CA013696NCI NIH HHS R01 CA248315NCI NIH HHS R01 CA250173NHLBI NIH HHS R01 HL152446NHLBI NIH HHS T32 HL007843NIDDK NIH HHS R01 DK060694NIGMS NIH HHS R37 GM056328
6 · The paper itself

Abstract

The mitochondrial uniporter (MCU) Ca

Identifiers

PMID37163088
PMCPMC10168388
OpenAlexW4367302862

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.