ArticleResearch square2023
Type III CRISPR-Cas complexes act as protein-assisted ribozymes during target RNA cleavage.
Evan A Schwartz, Jack P K Bravo, Mohd Ahsan, Luis A Macias, Caitlyn L McCafferty, Tyler L Dangerfield, Jada N Walker, Jennifer S Brodbelt, Giulia Palermo, Peter C Fineran and 2 more
Open access · greenAbstract readPreprint
In one paragraphArticle in Research square, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 3 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
12 authors at 3 institutions in 2 countries.
Evan A SchwartzInterdisciplinary Life Sciences Graduate Programs, University of Texas at Austin.
Jack P K BravoDepartment of Molecular Biosciences, University of Texas at Austin.
Mohd AhsanDepartment of Bioengineering and Department of Chemistry, University of California, Riverside.
Luis A MaciasDepartment of Chemistry, University of Texas at Austin.
Caitlyn L McCaffertyInterdisciplinary Life Sciences Graduate Programs, University of Texas at Austin.
Tyler L DangerfieldDepartment of Molecular Biosciences, University of Texas at Austin.
Jennifer S BrodbeltDepartment of Chemistry, University of Texas at Austin.
Giulia PalermoDepartment of Bioengineering and Department of Chemistry, University of California, Riverside.
Peter C FineranMicrobiology and Immunology, University of Otago, PO Box 56, Dunedin 9054, New Zealand.ORCID 0000-0002-4639-6704 Robert D FagerlundMicrobiology and Immunology, University of Otago, PO Box 56, Dunedin 9054, New Zealand.ORCID 0000-0002-3939-1489 The University of Texas at Austin · USUniversity of California, Riverside · USUniversity of Otago · NZ
Funding
Ultraviolet Photodissociation Mass Spectrometry for Characterization of Biological MoleculesR35GM139658 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI BRODBELT, JENNIFER S. · 2021 to 2025
$2.9MImaging macromolecular machines in gene regulationR35GM138348 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI TAYLOR, DAVID W · 2020 to 2024
$1.9MInvestigating the metal-dependent function, allostery and inhibition of CRISPR-Cas9R01GM141329 · NIGMS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI PALERMO, GIULIA · 2021 to 2025
$1.7MImplementing Photodissociation Mass Spectrometry to study Disease and Lipid StructureF31CA257404 · NCI · UNIVERSITY OF TEXAS AT AUSTIN · PI MACIAS, LUIS A · 2021 to 2022
$49kNCI NIH HHS F31 CA257404NIGMS NIH HHS R01 GM141329NIGMS NIH HHS R35 GM138348NIGMS NIH HHS R35 GM139658
6 · The paper itselfAbstract
CRISPR-Cas systems are an adaptive immune system in bacteria and archaea that utilize CRISPR RNA-guided surveillance complexes to target complementary RNA or DNA for destruction
Identifiers
PMID37163044
PMCPMC10168453
OpenAlexW4367183428
What OpenQuestion holds
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LicenceCC BY
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