Evidence map›Paper›PMID 37162990›Full record

ArticlebioRxiv : the preprint server for biology2024

CD3

Laventa M Obare, Joshua Simmons, Jared Oakes, Xiuqi Zhang, Cindy Nochowicz, Stephen Priest, Samuel S Bailin, Christopher M Warren, Mona Mashayekhi, Heather K Beasley and 22 more

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

32 authors at 8 institutions in 2 countries.

Laventa M ObareDivision of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
Joshua SimmonsDivision of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
Jared OakesDivision of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
Xiuqi ZhangDivision of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
Cindy NochowiczDivision of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
Stephen PriestDivision of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
Samuel S BailinDivision of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
Christopher M WarrenVeterans Affairs Tennessee Valley Healthcare System, Nashville, TN, USA.
Mona MashayekhiDivision of Diabetes, Endocrinology, and Metabolism, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0003-0331-2395
Heather K BeasleyDepartment of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.
Jianqiang ShaoCentral Microscopy Research Facility, University of Iowa, Iowa City, IA, USA.
Leslie M MeenderinkDivision of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
Quanhu ShengDepartment of Biostatistics, Vanderbilt University, Nashville, TN, USA.
Joey StolzeDepartment of Biostatistics, Vanderbilt University, Nashville, TN, USA.
Rama GangulaDivision of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
Tarek AbsiDepartment of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Yan Ru SuDepartment of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Kit NeikirkDepartment of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.
Abha ChopraInstitute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Western Australia, Australia.
Curtis L GabrielDivision of Gastroenterology, Vanderbilt University Medical Center, Nashville, TN, USA.
Tecla TemuDepartment of Global Health, University of Washington, Seattle, WA, USA.
Suman PakalaDivision of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
Erin M WilfongDivision of Rheumatology and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.
Sara GianellaDivision of Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA.
Elizabeth J PhillipsDivision of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
David G HarrisonDivision of Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA.
Antentor HintonDepartment of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.ORCID 0000-0002-7730-952X
Spyros A KalamsDivision of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
Annet KiraboDepartment of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.
Simon A MallalDivision of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
John R KoetheDivision of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.
Celestine N WanjallaDivision of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0001-9159-5414
Vanderbilt University Medical Center · USVanderbilt University · USMurdoch University · AUVA Tennessee Valley Healthcare System · USDiabetes Australia · AUUniversity Medical Center · USUniversity of Iowa · USUniversity of Washington · US

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STACIE B DUSETZINA · 1995 to 2026
$172.8M
HOPE - HIV Obstruction by Programmed EpigeneticsUM1AI164559 · NIAID · J. DAVID GLADSTONE INSTITUTES · PI Lishomwa C Ndhlovu, Melanie Maria Ott · 2021 to 2026
$32.2M
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Vanderbilt Diabetes Research CenterP30DK020593 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALVIN C POWERS · 2012 to 2026
$29.3M
Tennessee CFAR: Implementation of Culturally Responsive Trauma-Informed Care with Youth with HIV in Memphis, TNP30AI110527 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI John Koethe · 2015 to 2026
$27.5M
Training In Cardiovascular Physiology & PharmacologyT32HL007444 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ju Chen, Robert Scott Ross · 1985 to 2026
$11.1M
Institutional Career Development CoreKL2TR002245 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Julie A. Bastarache · 2017 to 2026
$9.3M
PRIDE: Functional and Translational Genomics of Blood DisordersR25HL106365 · NHLBI · AUGUSTA UNIVERSITY · PI PACE, BETTY SUE · 2010 to 2024
$5.2M
The Role of Adipose-Resident T Cells in HIV-Associated Glucose IntoleranceR01DK112262 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KOETHE, JOHN · 2017 to 2021
$3.8M
UCSD PRIDE Faculty Development Program in Cardiovascular SciencesR25HL145817 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Robert Scott Ross, Joann Trejo · 2019 to 2026
$3.3M
Immune Mechanisms of Salt-Sensitive hypertensionR01HL144941 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KIRABO, ANNET · 2021 to 2025
$3.0M
Vanderbilt SCHolars in HIV and Heart, Lung, Blood, and Sleep ReSearch (V-SCHoLARS, K12)K12HL143956 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI FREIBERG, MATTHEW S, KOETHE, JOHN · 2018 to 2022
$1.6M
BLRD VA IK2 BX004885NCATS NIH HHS KL2 TR002245NCI NIH HHS P30 CA068485NHLBI NIH HHS K12 HL143956NHLBI NIH HHS K23 HL156759NHLBI NIH HHS K23 HL159351NHLBI NIH HHS R01 HL144941NHLBI NIH HHS R03 HL155041NHLBI NIH HHS R25 HL106365NHLBI NIH HHS R25 HL145817NHLBI NIH HHS T32 HL007444NIAID NIH HHS P30 AI110527NIAID NIH HHS UM1 AI164559NIAMS NIH HHS K08 AR080808NIDDK NIH HHS P30 DK020593NIDDK NIH HHS P30 DK058404NIDDK NIH HHS R01 DK112262
6 · The paper itself

Abstract

An increased risk of cardiometabolic disease accompanies persistent systemic inflammation. Yet, the innate and adaptive immune system features in persons who develop these conditions remain poorly defined. Doublets, or cell-cell complexes, are routinely eliminated from flow cytometric and other immune phenotyping analyses, which limits our understanding of their relationship to disease states. Using well-characterized clinical cohorts, including participants with controlled HIV as a model for chronic inflammation and increased immune cell interactions, we show that circulating CD14

Indexed as

CD3+T-cell:CD14+monocyte complexesdiabetesdoubletsHIVreservoir

Identifiers

PMID37162990
PMCPMC10168203
OpenAlexW4367040800

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.