Evidence map›Paper›PMID 37162946›Full record

ArticlebioRxiv : the preprint server for biology2023

Long lifetime and selective accumulation of the A-type lamins accounts for the tissue specificity of Hutchinson-Gilford progeria syndrome.

John Hasper, Kevin Welle, Kyle Swovick, Jennifer Hryhorenko, Sina Ghaemmaghami, Abigail Buchwalter

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

John HasperCardiovascular Research Institute, University of California, San Francisco, San Francisco, CA.
Kevin WelleUniversity of Rochester Mass Spectrometry Resource Laboratory, Rochester, NY.
Kyle SwovickUniversity of Rochester Mass Spectrometry Resource Laboratory, Rochester, NY.
Jennifer HryhorenkoUniversity of Rochester Mass Spectrometry Resource Laboratory, Rochester, NY.
Sina GhaemmaghamiUniversity of Rochester Mass Spectrometry Resource Laboratory, Rochester, NY.
Abigail BuchwalterCardiovascular Research Institute, University of California, San Francisco, San Francisco, CA.
University of Rochester · USUniversity of California, San Francisco · US

Funding

The prevalence and mechanism of selectivity in basal autophagyR35GM119502 · NIGMS · UNIVERSITY OF ROCHESTER · PI SINA GHAEMMAGHAMI · 2016 to 2026
$5.9M
Orbitrap Fusion Lumos Mass Spectrometer for UR Proteomics ResearchS10OD025242 · OD · UNIVERSITY OF ROCHESTER · PI GHAEMMAGHAMI, SINA · 2018 to 2018
$1.1M
NIGMS NIH HHS R35 GM119502NIH HHS S10 OD025242
6 · The paper itself

Abstract

Mutations to the

Indexed as

Biological SciencesCell Biologynuclear laminaprogeriaprotein homeostasis

Identifiers

PMID37162946
PMCPMC10168242
OpenAlexW4319265240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.