Evidence map›Paper›PMID 37162886›Full record

ArticlebioRxiv : the preprint server for biology2023

Protein homeostasis from diffusion-dependent control of protein synthesis and degradation.

Yuping Chen, Jo-Hsi Huang, Connie Phong, James E Ferrell

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 11 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yuping ChenDept. of Chemical and Systems Biology, Stanford University School of Medicine, Stanford CA 94305.
Jo-Hsi HuangDept. of Chemical and Systems Biology, Stanford University School of Medicine, Stanford CA 94305.
Connie PhongDept. of Chemical and Systems Biology, Stanford University School of Medicine, Stanford CA 94305.
James E FerrellDept. of Chemical and Systems Biology, Stanford University School of Medicine, Stanford CA 94305.
Stanford University · US

Funding

Cytoplasmic organization and systems-level function in Xenopus extractsR35GM131792 · NIGMS · STANFORD UNIVERSITY · PI JAMES E. FERRELL · 2019 to 2026
$5.6M
NIGMS NIH HHS R35 GM131792
6 · The paper itself

Abstract

It has been proposed that the concentration of proteins in the cytoplasm maximizes the speed of important biochemical reactions. Here we have used the

Indexed as

Cytoplasmic concentrationdiffusion controlmaximal speed conjecturemolecular crowdingprotein homeostasisprotein synthesis and degradationviscosityXenopus egg extract

Identifiers

PMID37162886
PMCPMC10168264
OpenAlexW4367302261

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.