Evidence map›Paper›PMID 37162661›Full record

ReviewCurrent psychiatry reports2023

Sex-Based Contributors to and Consequences of Post-traumatic Stress Disorder.

Lucy V Hiscox, Tamsin H Sharp, Miranda Olff, Soraya Seedat, Sarah L Halligan

Open access · hybridAbstract readReview
In one paragraph

Review in Current psychiatry reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
14.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
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  5. Nucleus accumbens medial shell D1 and D2 medium spiny neurons signal the valence of conditioned stimuli in a sex-dependent manner.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
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  7. Review
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  19. Rat Models in Post-Traumatic Stress Disorder Research: Strengths, Limitations, and Implications for Translational Studies.Pathophysiology : the official journal of the International Society for Pathophysiology · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Lucy V HiscoxDepartment of Psychology, University of Bath, Bath, UK.ORCID 0000-0001-6296-7442
Tamsin H SharpDepartment of Psychology, University of Bath, Bath, UK.ORCID 0000-0002-7334-0503
Miranda OlffDepartment of Psychiatry, Amsterdam University Medical Centers, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0003-1016-9515
Soraya SeedatDepartment of Psychiatry, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.ORCID 0000-0002-5118-786X
Sarah L HalliganDepartment of Psychology, University of Bath, Bath, UK. slh54@bath.ac.uk.ORCID 0000-0002-3436-3358
University of Bath · GBAmsterdam UMC Location University of Amsterdam · NLStellenbosch University · ZAUniversity of Cape Town · ZA

Funding

Medical Research Council MR/T002816/1
6 · The paper itself

Abstract

purpose of reviewWomen are twice as likely to develop post-traumatic stress disorder (PTSD) compared to men after a traumatic experience. The purpose of this mini review was to explore recent research on biological contributors to this sex difference. RECENT

findingsWe identified 51 studies published since 2019. Studies found that beyond the influence of sex on the prevalence and symptoms of PTSD, there is evidence for and against sex-based differences in genetic and epigenetic factors (n = 8), brain structure and function (n = 11), neuroendocrine and inflammatory responses (n = 5), and in the role of sleep on emotional memory processing (n = 1). Sex differences were also observed in recovery and during PTSD treatment (n = 16). Finally, there is emerging evidence of sex-differentiated risk for medical and psychiatric comorbidities in PTSD (n = 10). Rapid advances are being made using integrated multidisciplinary approaches to understand why females are at a heightened risk for developing PTSD.

Indexed as

Stress Disorders, Post-TraumaticBrainComorbidityEmotionsFemaleHumansMaleSex CharacteristicsPost-traumatic stressPTSDSex characteristicsSex differencesTrauma

Identifiers

PMID37162661
PMCPMC10188381
OpenAlexW4376121763

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.