Evidence map›Paper›PMID 37162627›Full record

ArticleBulletin of experimental biology and medicine2023

Influence of Paleobacteria on the Proliferative Activity of Human Lymphocytes In Vitro.

L F Kalenova, S A Petrov, A M Subbotin, M V Narushko, A S Bazhin

Abstract read
PubMed Publisher
In one paragraph

Article in Bulletin of experimental biology and medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

L F KalenovaTyumen Research Center, Siberian Division of the Russian Academy of Sciences, Tyumen, Russia. lkalenova@mail.ru.
S A PetrovTyumen Research Center, Siberian Division of the Russian Academy of Sciences, Tyumen, Russia.
A M SubbotinTyumen Research Center, Siberian Division of the Russian Academy of Sciences, Tyumen, Russia.
M V NarushkoTyumen Research Center, Siberian Division of the Russian Academy of Sciences, Tyumen, Russia.
A S BazhinTyumen Research Center, Siberian Division of the Russian Academy of Sciences, Tyumen, Russia.
Siberian Branch of the Russian Academy of Sciences · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

When testing the proliferative activity of 14 strains of permafrost microorganisms in the reaction of blast transformation of human lymphocytes in vitro, a strain (Alcaligenes sp.) with mitogen properties was isolated (20-fold increase in the rate of lymphocyte proliferation in comparison with the control). Four strains activated lymphocyte proliferation by 3-9 times in comparison with the control. Three strains produced substances with cytostatic properties and reduced proliferation activity by 33-43% and one strain (Bacillus sp.) almost completely suppressed phytohemagglutinin-induced lymphocyte proliferation. These data indicate that strains with a unique immunobiological potential are concentrated in the population of permafrost microorganisms that have undergone rigorous evolutionary selection.

Indexed as

LymphocytesMitogensHumansLymphocyte ActivationPhytohemagglutininsMitogensPhytohemagglutininscytostaticslymphocyte blast transformation reactionmitogenspaleobacteria antigenspermafrost microorganisms

Identifiers

PMID37162627
OpenAlexW4376121662

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.