Evidence map›Paper›PMID 37162236›Full record

ArticleEnvironmental health perspectives2023

Early-Life Exposure to Ambient Air Pollution from Multiple Sources and Asthma Incidence in Children: A Nationwide Birth Cohort Study from Denmark.

Marie Pedersen, Shuo Liu, Jiawei Zhang, Zorana Jovanovic Andersen, Jørgen Brandt, Esben Budtz-Jørgensen, Klaus Bønnelykke, Lise Marie Frohn, Anne-Marie Nybo Andersen, Matthias Ketzel and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Environmental health perspectives, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 3 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Chemical constituents of PMEuropean journal of pediatrics · 2025
    Pooled it
  3. Childhood asthma and mould in homes-A meta-analysis.Wiener klinische Wochenschrift · 2025
    Pooled it
  4. Adverse Effects of Carbon Black Nanoparticles on Maternal and Fetal Lungs in Pregnant Mice: Insights From a Metabolomics Perspective.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
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  10. Long-term exposures to PMBMC cancer · 2025
    Article
  11. PMEnvironment & health (Washington, D.C.) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 4 countries.

Marie PedersenDepartment of Public Health, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-9930-0446
Shuo LiuDepartment of Public Health, University of Copenhagen, Copenhagen, Denmark.
Jiawei ZhangDepartment of Public Health, University of Copenhagen, Copenhagen, Denmark.
Zorana Jovanovic AndersenDepartment of Public Health, University of Copenhagen, Copenhagen, Denmark.
Jørgen BrandtDepartment of Environmental Science, Aarhus University, Roskilde, Denmark.
Esben Budtz-JørgensenDepartment of Public Health, University of Copenhagen, Copenhagen, Denmark.
Klaus BønnelykkeCopenhagen Prospective Studies on Asthma in Childhood (COPSAC), Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.
Lise Marie FrohnDepartment of Environmental Science, Aarhus University, Roskilde, Denmark.
Anne-Marie Nybo AndersenDepartment of Public Health, University of Copenhagen, Copenhagen, Denmark.
Matthias KetzelDepartment of Environmental Science, Aarhus University, Roskilde, Denmark.
Jibran KhanDepartment of Environmental Science, Aarhus University, Roskilde, Denmark.
Leslie StaynerSchool of Public Health, University of Illinois at Chicago, Chicago, USA.
Bert BrunekreefInstitute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.
Steffen LoftDepartment of Public Health, University of Copenhagen, Copenhagen, Denmark.
University of Copenhagen · DKAarhus University · DKRoskilde University · DKUniversity of Illinois Chicago · USUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAmbient air pollution exposure has been associated with childhood asthma, but previous studies have primarily focused on prevalence of asthma and asthma-related outcomes and urban traffic-related exposures.

objectiveWe examined nationwide associations between pre- and postnatal exposure to ambient air pollution components and asthma incidence in children age 0-19 y.

methodsAsthma incidence was identified from hospital admission, emergency room, and outpatient contacts among all live-born singletons born in Denmark between 1998 and 2016. We linked registry data with monthly mean concentrations of particulate matter (PM) with aerodynamic diameter

resultsOf the 1,060,154 children included, 6.1% had asthma during the mean follow-up period of 8.8 y. The risk of asthma increased with increasing prenatal exposure to all pollutants except for DISCUSSION: These findings suggest that early-life exposure to ambient air pollution from multiple sources contributes to asthma development. https://doi.org/10.1289/EHP11539.

Indexed as

Air PollutantsAir PollutionAsthmaEnvironmental PollutantsPrenatal Exposure Delayed EffectsAdolescentAdultCarbonChildChild, PreschoolCohort StudiesDenmarkEnvironmental ExposureFemaleHumansIncidenceAir PollutantsCarbonEnvironmental PollutantsNitrogen DioxideParticulate Matter

Identifiers

PMID37162236
PMCPMC10171081
OpenAlexW4376122112

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.