Evidence map›Paper›PMID 37162036›Full record

ReviewAJR. American journal of roentgenology2024

MR Elastography: Practical Questions, From the

Meng Yin, Richard L Ehman

Open access · greenAbstract readReview
In one paragraph

Review in AJR. American journal of roentgenology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Article
  3. Kidney Elastography in Adult Nephrology: A Narrative Review.Diagnostics (Basel, Switzerland) · 2026
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Real-World Assessment of Liver Corrected T1 and Magnetic Resonance Elastography in Predicting Liver Disease Progression.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Meng YinDepartment of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55902.
Richard L EhmanDepartment of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55902.
Mayo Clinic · US

Funding

Comprehensive noninvasive assessment of liver histopathology in nonalcoholic fatty liver disease (NAFLD) via magnetic resonance imaging, cytometry and elastography (MR-ICE)R01EB017197 · NIBIB · MAYO CLINIC ROCHESTER · PI YIN, MENG · 2014 to 2025
$4.3M
Magnetic Resonance ElastographyR37EB001981 · NIBIB · MAYO CLINIC ROCHESTER · PI EHMAN, RICHARD L. · 2016 to 2025
$4.0M
Quantitative characterization of the liver-pancreas axis in diabetes via multiparametric magnetic resonance elastographyR01DK136731 · NIDDK · MAYO CLINIC ROCHESTER · PI Meng Yin · 2023 to 2026
$1.6M
Noninvasive assessment of portal hypertension and hepatic interstitial pressure with advanced magnetic resonance elastographyR01DK132718 · NIDDK · MAYO CLINIC ROCHESTER · PI Meng Yin · 2023 to 2026
$1.3M
Assessment of Alcoholic Hepatitis with Multiparametric Magnetic Resonance ElastographyUH3AA026887 · NIAAA · MAYO CLINIC ROCHESTER · PI SHAH, VIJAY H., YIN, MENG · 2020 to 2022
$1.1M
Noninvasive assessment of alcoholic hepatitis effects in promoting age-related cognitive decline with multiparametric magnetic resonance elastography (MRE) imagingUH2AA026887 · NIAAA · MAYO CLINIC ROCHESTER · PI SHAH, VIJAY H., YIN, MENG · 2018 to 2019
$653k
NIAAA NIH HHS UH2 AA026887NIAAA NIH HHS UH3 AA026887NIBIB NIH HHS R01 EB017197NIBIB NIH HHS R37 EB001981NIDDK NIH HHS R01 DK132718NIDDK NIH HHS R01 DK136731
6 · The paper itself

Abstract

MR elastography (MRE), first described in 1995 and FDA-cleared in 2009, has emerged as an important tool for noninvasively detecting and staging liver fibrosis in patients with known or suspected chronic liver disease. This review focuses on a series of practical questions about the clinical use of MRE. Most head-to-head comparison studies with other laboratory and imaging-based tests have concluded that MRE has the highest diagnostic performance among tests for staging liver fibrosis. Limitations in the accuracy of biopsy as a standard of truth in staging liver fibrosis are increasingly being recognized. MRE-based measurements show promise as quantitative surrogates of disease severity and predictors of important clinical outcomes. The appropriate role of MRE in the management of patients with chronic liver disease is being actively incorporated into recognized clinical guidelines. Growing evidence shows that MRI measurement of elevated liver fat is the most important single biomarker for detecting nonalcoholic steatohepatitis (NASH) and that MRE-based liver stiffness is the most important single biomarker for detecting at-risk NASH (i.e., NASH with stage ≥ F2 fibrosis). Advances in MRE technology are offering higher precision and new biomarkers, which have potential to allow independent assessment of inflammation and other histologic processes in addition to fibrosis.

Indexed as

Elasticity Imaging TechniquesNon-alcoholic Fatty Liver DiseaseBiomarkersHumansLiverLiver CirrhosisMagnetic Resonance ImagingReproducibility of ResultsBiomarkersliver fibrosisMR elastography

Identifiers

PMID37162036
PMCPMC10636243
OpenAlexW4376114524

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.