ArticleInternational health2024
Differential effects of size-specific particulate matter on frailty transitions among middle-aged and older adults in China: findings from the China Health and Retirement Longitudinal Study (CHARLS), 2015-2018.
Article in International health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review and meta-analysis of air pollution and increased risk of frailty.Age and ageing · 2025Pooled it
- [Effect of Long-term Exposure to PMSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026Article
- Community-dwelling older persons' level of functional ability and heat-related vulnerability: results from the Heat-Health Action Plan study in Cologne, Germany.BMC geriatrics · 2026Article
- Traffic-related air pollutant exposure and physical performance in the Adult Changes in Thought cohort.Environment international · 2025Article
- Lifestyle, environment and other major determinants of frailty in older adults: a population-based study from the UK Biobank.Biogerontology · 2025Article
- Causal association between air pollution and frailty: a Mendelian randomization study.Frontiers in public health · 2023Article
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Authors and funding
9 authors.
Funding
Abstract
backgroundThis study aimed to assess the long-term effects of size-specific particulate matter (PM) on frailty transitions in middle-aged and older Chinese adults.
methodsWe included 13 910 participants ≥45 y of age from the China Health and Retirement Longitudinal Study (CHARLS) for 2015 and 2018 who were classified into three categories in 2015 according to their frailty states: robust, prefrail and frail. Air quality data were obtained from the National Urban Air Quality Real-time Publishing Platform. A two-level logistic regression model was used to examine the association between concentrations of PM and frailty transitions.
resultsAt baseline, the total number of robust, prefrail and frail participants were 7516 (54.0%), 4324 (31.1%) and 2070 (14.9%), respectively. Significant associations were found between PM concentrations and frailty transitions. For each 10 μg/m3 increase in the 3-y averaged 2.5-μm PM (PM2.5) concentrations, the risk of worsening in frailty increased in robust (odds ratio [OR] 1.06 [95% confidence interval {CI} 1.01 to 1.12]) and prefrail (OR 1.07 [95% CI 1.01 to 1.13]) participants, while the probability of improvement in frailty in prefrail (OR 0.91 [95% CI 0.84 to 0.98]) participants decreased. In addition, the associations of PM10 and coarse fraction of PM with frailty transitions showed similar patterns.
conclusionsLong-term exposure to PM was associated with higher risks of worsening and lower risks of improvement in frailty among middle-aged and older adults in China.
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