Evidence map›Paper›PMID 37161925›Full record

ArticleCancer control : journal of the Moffitt Cancer Center

RNA-Sequencing Combined With Genome-Wide Allele-Specific Expression Patterning Identifies ZNF44 Variants as a Potential New Driver Gene for Pediatric Neuroblastoma.

Lan Sun, Xiaoqing Li, Lingli Tu, Andres Stucky, Chuan Huang, Xuelian Chen, Jin Cai, Shengwen Calvin Li

Open access · goldAbstract read
In one paragraph

Article in Cancer control : journal of the Moffitt Cancer Center. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Lan SunDepartment of Oncology,Bishan Hospital of Chongqing Medical University, The People's Hospital of Bishan District, Chongqing, China.
Xiaoqing LiDepartment of Oncology,Bishan Hospital of Chongqing Medical University, The People's Hospital of Bishan District, Chongqing, China.
Lingli TuDepartment of Otolaryngology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Andres StuckyDepartment of Otolaryngology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Chuan HuangDepartment of Oncology,Bishan Hospital of Chongqing Medical University, The People's Hospital of Bishan District, Chongqing, China.
Xuelian ChenDepartment of Otolaryngology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Jin CaiDepartment of Oral and Maxillofacial Surgery, Zhuhai People's Hospital, Zhuhai Hospital Affiliated with Jinan University, Zhuhai, China.
Shengwen Calvin LiNeuro-Oncology and Stem Cell Research Laboratory, Center for Neuroscience Research, CHOC Children's Research Institute, Children's Hospital of Orange County (CHOC), Orange, CA, USA.ORCID 0000-0002-9699-9204
People's Hospital of Bishan District · CNUniversity of Southern California · USChildren's Hospital of Orange County · USJinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNeuroblastoma (NB) is one of the children's most common solid tumors, accounting for approximately 8% of pediatric malignancies and 15% of childhood cancer deaths. Somatic mutations in several genes, such as

methodsThis study analyzed 219 whole-exome sequencing datasets with somatic mutations detected by MuTect from paired normal and tumor samples.

resultsWe prioritized mutations in 8 candidate genes (

conclusionOur study suggests 2 novel variants of

Indexed as

NeuroblastomaRNAAllelesCarrier ProteinsChildCyclic Nucleotide-Gated Cation ChannelsHumansN-Myc Proto-Oncogene ProteinReceptor Protein-Tyrosine KinasesCarrier ProteinsCNGB1 protein, humanCyclic Nucleotide-Gated Cation ChannelsN-Myc Proto-Oncogene ProteinReceptor Protein-Tyrosine KinasesRNARUSC2 protein, humanallele-specific expression patternneuroblastomaRNA-seqsomatic mutationwhole-exome sequencingZNF44

Identifiers

PMID37161925
PMCPMC10185978
OpenAlexW4376131524

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.