Evidence map›Paper›PMID 37161406›Full record

ArticleBMC women's health2023

Factors associated with self-report of polycystic ovary syndrome in the Coronary Artery Risk Development in Young Adults study (CARDIA).

Catherine Kim, Pamela J Schreiner, David Siscovick, Ange Wang, Melissa F Wellons, Imo Ebong, Thanh-Huyen Vu, Duke Appiah, Janet Catov, Enrique F Schisterman and 2 more

Abstract read
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In one paragraph

Article in BMC women's health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Catherine KimDepartments of Medicine, Obstetrics & Gynecology, and Epidemiology, University of Michigan, North Campus Research Center, 2800 Plymouth Road, Building 16, Room 405E, Ann Arbor, MI, 48109, USA. cathkim@umich.edu.
Pamela J SchreinerDivision of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA.
David SiscovickNew York Academy of Medicine, New York City, NY, USA.
Ange WangDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of California San Francisco, San Francisco, CA, USA.
Melissa F WellonsDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Imo EbongDepartment of Medicine, University of California, Davis, Sacramento, CA, USA.
Thanh-Huyen VuDepartment of Preventive Medicine, Northwestern University, Chicago, IL, USA.
Duke AppiahDepartment of Public Health, School of Public and Population Health, Texas Tech University Health Sciences Center, Lubbock, TX, USA.
Janet CatovDepartment of Obstetrics, Gynecology & Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA, USA.
Enrique F SchistermanDepartment of Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Zhe YinInstitute of Health Policy and Innovation, University of Michigan, Ann Arbor, MI, USA.
Cora E LewisDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA.

Funding

Androgens and subclinical atherosclerosis in young womenR01HL065622 · NHLBI · UNIVERSITY OF WASHINGTON · PI SISCOVICK, DAVID · 2001 to 2003
$3.8M
Abnormalities in androgens and ovarian markers in reproductive-age racially and ethnically diverse women in a prospective longitudinal cohortR56HL169167 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KIM, CATHERINE · 2023 to 2023
$761k
Increased Cardiovacular Risk and Early Natural Menopause in a Biracial CohortK23HL087114 · NHLBI · VANDERBILT UNIVERSITY · PI WELLONS, MELISSA FAIR · 2008 to 2012
$744k
Shared Antecedents to Pre-term Birth and Cardiovascular Disease in WomenR21HL145419 · NHLBI · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI CATOV, JANET M · 2019 to 2020
$503k
Beneficial effects of childhood vaccines for prevention of type 1 diabetes, autoimmune thyroid disease, and celiac diseaseR21DK128586 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KIM, CATHERINE · 2021 to 2022
$429k
Trajectory of Anti-Mullerian Hormone Decline and CVD Risk in CARDIA WomenR03HL135453 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WELLONS, MELISSA FAIR · 2016 to 2017
$167k
NHLBI NIH HHS HHSN268201800003INHLBI NIH HHS HHSN268201800004INHLBI NIH HHS HHSN268201800005INHLBI NIH HHS HHSN268201800006INHLBI NIH HHS HHSN268201800007INHLBI NIH HHS K23 HL087114NHLBI NIH HHS R01 HL065622NHLBI NIH HHS R03 HL135453NHLBI NIH HHS R21 HL145419NHLBI NIH HHS R56 HL169167NIDDK NIH HHS R21 DK128586
6 · The paper itself

Abstract

backgroundPolycystic ovary syndrome (PCOS) is underdiagnosed, but factors associated with women's report of diagnosis are not well-understood, particularly social determinants of health. Therefore, in a population-based cohort, we compared the characteristics of women with self-reported PCOS vs. women who have unrecognized PCOS vs. women without PCOS.

methodsWe performed a secondary data analysis of the Coronary Artery Risk Development in Young Adults (CARDIA) Study, a population-based, prospective cohort of Black and White women. Participants were women (n = 2028) who responded to the question, "Did a doctor or nurse ever tell you that you had polycystic ovarian syndrome or polycystic ovarian disease?" at the year 15 examination. Women who answered "yes" were defined as having self-reported PCOS. Women who answered "no or not sure" were defined as having unrecognized PCOS if they also had irregular menses and hyperandrogenemia between 20 and 30 years of age. Exposures of interest included social determinants of health, symptoms including irregular menses and hirsutism, and comorbid conditions.

resultsForty-three (2.1%) of women had self-reported PCOS, 135 (6.7%) had unrecognized PCOS, and 1850 (91%) women were without PCOS. In logistic regression models adjusting for age, race, and center, women with self-reported PCOS were more likely to have obesity (OR 1.83, 95% CI 1.22, 2.75) and diabetes (OR 2.37, 95% CI 1.05, 5.33) compared to women without PCOS. Women with unrecognized PCOS were more likely to have hypertension (OR 1.68, 95% CI 1.03, 2.74) and food insecurity (OR 1.94, 95% CI 1.25, 3.01) compared to women without PCOS.

conclusionsUnrecognized PCOS is common. Self-report of PCOS is not associated with access to healthcare. Women who report PCOS are more often obese and comorbidities may contribute to recognition of PCOS.

Indexed as

Polycystic Ovary SyndromeAdultBlack or African AmericanBlack PeopleCoronary VesselsFemaleHeart Disease Risk FactorsHumansObesityProspective StudiesSelf ReportWhiteYoung AdultDiagnosisPolycystic ovary syndromeSelf-report

Identifiers

PMID37161406
PMCPMC10170674

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.