Evidence map›Paper›PMID 37161364›Full record

ArticleGenetics, selection, evolution : GSE2023

Characterization of the genetic pool of the Canadienne dairy cattle breed.

Alexandra Carrier, Isabelle Gilbert, Pierre Leclerc, Mario Duchesne, Claude Robert

Open access · goldAbstract read
In one paragraph

Article in Genetics, selection, evolution : GSE, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Alexandra CarrierCentre de recherche en reproduction, développement et santé intergénérationnelle, Université Laval, Québec, QC, Canada.
Isabelle GilbertCentre de recherche en reproduction, développement et santé intergénérationnelle, Université Laval, Québec, QC, Canada.
Pierre LeclercCentre de recherche en reproduction, développement et santé intergénérationnelle, Université Laval, Québec, QC, Canada.
Mario DuchesneAssociation de Mise en Valeur de La Race Bovine Canadienne (AVRBC), Québec, QC, Canada.
Claude RobertCentre de recherche en reproduction, développement et santé intergénérationnelle, Université Laval, Québec, QC, Canada. claude.robert@fsaa.ulaval.ca.ORCID http://orcid.org/0000-0001-9690-8088
Ministère de l'Agriculture, des Pêcheries et de l'Alimentation · CACanadian Association for Co-operative Education · CAUniversité Laval · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCanadienne cattle are the oldest breed of dairy cattle in North America. The Canadienne breed originates from cattle that were brought to America by the mid-seventeenth century French settlers. The herd book was established in 1886 and the current breed characteristics include dark coat color, small size compared to the modern Holstein breed, and overall rusticity shaped by the harsh environmental conditions that were prevalent during the settlement of North America. The Canadienne breed is an invaluable genetic resource due to its high resilience, longevity and fertility. However, it is heavily threatened with a current herd limited to an estimated 1200 registered animals, of which less than 300 are fullblood. To date, no effort has been made to document the genetic pool of this heritage breed in order to preserve it.

resultsIn this project, we used genomic data, which allow a precise description of the genetic makeup of a population, to provide valuable information on the genetic diversity of this heritage breed and suggest management options for its long-term viability. Using a panel that includes 640,000 single nucleotide polymorphisms (SNPs), we genotyped 190 animals grouped into six purity ranges. Unsupervised clustering analyses revealed three genetically distinct groups among those with the higher levels of purity. The observed heterozygosity was higher than expected even in the 100% purebreds. Comparison with Holstein genotypes showed significantly shorter runs of homozygosity for the Canadienne breed, which was unexpected due to the high inbreeding value calculated from pedigree data.

conclusionsOverall, our data indicate that the fullblood gene pool of the Canadienne breed is more diversified than expected and that bloodline management could promote breed sustainability. In its current state, the Canadienne is not a dead-end breed but remains highly vulnerable due to its small population size.

Indexed as

Gene PoolInbreedingAnimalsCattleFertilityGenomicsGenotype

Identifiers

PMID37161364
PMCPMC10170705
OpenAlexW4376132879

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.