ArticleBMC plant biology2023
Combined transcriptomic and metabolomic analyses elucidate key salt-responsive biomarkers to regulate salt tolerance in cotton.
Article in BMC plant biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 40 citations in OpenAlex.
- Integrated transcriptomic and metabolomic analysis reveals the salt tolerance mechanisms in Lagerstroemia indica.BMC plant biology · 2026Article
- Mining and Analysis of Salt Tolerance Genes in Maize at the Seedling Stage.Current issues in molecular biology · 2026Article
- Metabolomic insights into the mechanisms of chickpea milkvetch (Astragalus Cicer L.) response to salt stress.BMC plant biology · 2026Article
- Integrated transcriptomic and metabolomic identification of the core pathway of photosynthetic carbon fixation in mung bean under saline-alkali stress.Frontiers in plant science · 2026Article
- Integrated transcriptomic and metabolomic analyses reveal biphasic thermal adaptation strategies inPeerJ · 2026Article
- Dual modulation of toxic risks and functional benefits: How traditional practices enable safe consumption of toxicFrontiers in plant science · 2026Article
- Enhanced nitrogen dynamics and uptake in cotton via organic liquid fertilizer partial substitution.Frontiers in plant science · 2026Article
- Genome-Wide Identification and Abiotic Stress-Responsive Expression Analysis of theLife (Basel, Switzerland) · 2025Article
- Untargeted metabolomics reveals key metabolites and genes underlying salinity tolerance mechanisms in maize.The plant genome · 2025Article
- Progress in Transcriptomics and Metabolomics in Plant Responses to Abiotic Stresses.Current issues in molecular biology · 2025Review
- Physiological and Metabolic Responses of Wheat (ACS agricultural science & technology · 2025Article
- Combined transcriptomic and metabolomic analysis revealed the salt tolerance mechanism of Populus talassica × Populus euphratica.BMC plant biology · 2025Article
- Comparative physiological and co-expression network analysis reveals potential hub genes and adaptive mechanisms responsive to NaCl stress in peanut (Arachis hypogaea L.).BMC plant biology · 2025Article
- Metabolic and Photosynthesis Analysis of Compound-Material-Mediated Saline and Alkaline Stress Tolerance in Cotton Leaves.Plants (Basel, Switzerland) · 2025Article
- Analysis of germination characteristics and metabolome ofFrontiers in plant science · 2025Article
- Molecular traits of MAPK kinases and the regulatory mechanism of GhMAPKK5 alleviating drought/salt stress in cotton.Plant physiology · 2024Article
- Article
- Genome-Wide Analysis of Aquaporins Gene Family inInternational journal of molecular sciences · 2024Article
- Influences of Salt Stress on Cotton Metabolism and Its Consequential Effects on the Development and Fecundity ofInsects · 2024Article
- Comparative transcriptomic and metabolomic analyses provide insights into the responses to high temperature stress in Alfalfa (Medicago sativa L.).BMC plant biology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
25 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCotton is an important industrial crop and a pioneer crop for saline-alkali land restoration. However, the molecular mechanism underlying the cotton response to salt is not completely understood.
methodsHere, we used metabolome data and transcriptome data to analyze the salt tolerance regulatory network of cotton and metabolic biomarkers.
resultsIn this study, cotton was stressed at 400 m M NaCl for 0 h, 3 h, 24 h and 48 h. NaCl interfered with cotton gene expression, altered metabolite contents and affected plant growth. Metabolome analysis showed that NaCl stress increased the contents of amino acids, sugars and ABA, decreased the amount of vitamin and terpenoids. K-means cluster analysis of differentially expressed genes showed that the continuously up-regulated genes were mainly enriched in metabolic pathways such as flavonoid biosynthesis and amino acid biosynthesis.
conclusionThe four metabolites of cysteine (Cys), ABA(Abscisic acid), turanose, and isopentenyladenine-7-N-glucoside (IP7G) were consistently up-regulated under salt stress, which may indicate that they are potential candidates for cotton under salt stress biomarkers. Combined transcriptome and metabolome analysis revealed accumulation of cysteine, ABA, isopentenyladenine-7-N-glucoside and turanose were important for salt tolerance in cotton mechanism. These results will provide some metabolic insights and key metabolite biomarkers for salt stress tolerance, which may help to understanding of the metabolite response to salt stress in cotton and develop a foundation for cotton to grow better in saline soil.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.