Evidence map›Paper›PMID 37161317›Full record

ArticleThe Journal of international medical research2023

Case report of extranodal natural killer/T-cell lymphoma that induced secondary hemophagocytic syndrome-related histiocytic glomerulopathy.

Fei Xiao, Shihui Hou, Kaizhen Kui, Xiaoyue Wang, Lihua Bai, Huanzi Dai

Open access · goldAbstract readCase Reports
In one paragraph

Article in The Journal of international medical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Fei XiaoDepartment of Nephrology, Daping Hospital, Army Medical University, Chongqing, China.
Shihui HouDepartment of Nephrology, Daping Hospital, Army Medical University, Chongqing, China.ORCID 0000-0003-4240-0275
Kaizhen KuiDepartment of Nephrology, Daping Hospital, Army Medical University, Chongqing, China.
Xiaoyue WangDepartment of Nephrology, Daping Hospital, Army Medical University, Chongqing, China.
Lihua BaiDepartment of Nephrology, Daping Hospital, Army Medical University, Chongqing, China.
Huanzi DaiDepartment of Rheumatology & Clinical Immunology, Daping Hospital, Army Medical University, Chongqing, China.
Army Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemophagocytic syndrome (HPS) is a proliferative disease of the mononuclear macrophage system involving multiple organs and systems. We report a 50-year-old Asian woman who presented with unexplained fever and proteinuria. Laboratory tests showed cytopenia, considerably elevated serum ferritin and IL-2 receptor concentrations, and evidence of hemophagocytosis in the bone marrow. A renal biopsy showed macrophage infiltration into the glomerulus, resulting in podocyte and endothelial cell damage. We finally diagnosed the patient with extranodal natural killer/T-cell lymphoma, nasal type that induced HPS-related histiocytic glomerulopathy. Proteinuria and inflammation responded to treatment with high-dose pulsed methylprednisolone combined with VP-16 and cyclosporine. To the best of our knowledge, this is the first documented case of HPS-related histiocytic glomerulopathy triggered by a malignant tumor.

Indexed as

Lymphohistiocytosis, HemophagocyticLymphoma, T-CellCyclosporineFemaleHumansKiller Cells, NaturalMacrophagesMiddle AgedCyclosporineextranodal natural killer/T-cell lymphomahemophagocytic syndromeHistiocytic glomerulopathypodocyte damageproteinuriarenal biopsy

Identifiers

PMID37161317
PMCPMC10184302
OpenAlexW4376131107

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.