Evidence map›Paper›PMID 37160975›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2023

Association of antenatal corticosteroids with kidney function in adolescents born preterm with very low birth weight.

Whitney N Floyd, Daniel P Beavers, Elizabeth T Jensen, Lisa K Washburn, Andrew M South

Open access · greenAbstract read
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Whitney N FloydWake Forest University School of Medicine, Winston-Salem, NC, 27101, USA.ORCID 0000-0003-0010-0047
Daniel P BeaversDepartment of Statistical Sciences, Wake Forest University, Winston-Salem, NC, 27101, USA.
Elizabeth T JensenDivision of Public Health Sciences, Department of Epidemiology and Prevention, Wake Forest University School of Medicine, Winston-Salem, NC, 27101, USA.
Lisa K WashburnDepartment of Pediatrics, Wake Forest University School of Medicine, Winston-Salem, NC, 27101, USA.
Andrew M SouthDivision of Public Health Sciences, Department of Epidemiology and Prevention, Wake Forest University School of Medicine, Winston-Salem, NC, 27101, USA. asouth@wakehealth.edu.ORCID 0000-0002-3204-4142
Wake Forest University · USBrenner Children's Hospital · US

Funding

WORKER PROTECTION AGAINST AIRBORNE INFLUENZA - A PILOT STUDYM01RR007122 · NCRR · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI WASHBURN, LISA K · 1992 to 2010
$35.2M
Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
The Impact of Antenatal Steroid Exposure on the Intrarenal Renin-Angiotensin SystP01HD047584 · NICHD · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ROSE, JAMES C. · 2005 to 2016
$13.0M
Uric Acid, Klotho and Salt Sensitivity in Young Adults Born PretermR01HL146818 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI CHAPPELL, MARK C, SHALTOUT, HOSSAM · 2019 to 2023
$4.0M
Wake Forest Short-term Research Training ProgramT35DK007400 · NIDDK · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI DONALD A. MCCLAIN · 1986 to 2026
$1.9M
The role of angiotensin-(1-7) in hypertension and hypertension-induced heart and kidney damageK23HL148394 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SOUTH, ANDREW MICHAEL · 2020 to 2024
$783k
Developmental Origins of Cardiovascular Disease in Offspring from Non-human Primate Pregnancies at Advanced Maternal AgeR56HL164434 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI CILVIK, SARAH N · 2022 to 2022
$708k
Novel Angiotensin-(1-7) Endopeptidase in Fetal ProgrammingR21HD084227 · NICHD · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI CHAPPELL, MARK C, ROSE, JAMES C. · 2016 to 2017
$426k
NCATS NIH HHS UL1 TR001420NCRR NIH HHS M01 RR007122NHLBI NIH HHS K23 HL148394NHLBI NIH HHS L40 HL148910NHLBI NIH HHS R01 HL146818NHLBI NIH HHS R56 HL164434NICHD NIH HHS P01 HD047584NICHD NIH HHS R21 HD084227NIDDK NIH HHS T35 DK007400
6 · The paper itself

Abstract

objectiveInvestigate if antenatal corticosteroids (ANCS) are associated with worse kidney function in adolescence and if greater adiposity magnifies this association. STUDY

designProspective cohort of 162 14-year-olds born preterm with very low birth weight (<1500 g). Outcomes were estimated glomerular filtration rate (eGFR) and first-morning urine albumin-to-creatinine ratio (UACR). We used adjusted generalized linear models, stratified by waist-to-height ratio (WHR) ≥ 0.5.

resultsFifty-five percent had ANCS exposure and 31.3% had WHR ≥ 0.5. In adjusted analyses of the entire cohort, ANCS was not significantly associated with eGFR or UACR. However, the ANCS-eGFR association was greater in those with WHR ≥ 0.5 (β -16.8 ml/min/1.73 m

conclusionANCS exposure was not associated with worse kidney function in adolescence, though ANCS may be associated with lower eGFR if children develop obesity by adolescence.

Indexed as

Infant, Very Low Birth WeightObesityAdolescentAdrenal Cortex HormonesChildCreatinineFemaleGlomerular Filtration RateHumansInfant, NewbornKidneyPregnancyProspective StudiesAdrenal Cortex HormonesCreatinine

Identifiers

PMID37160975
PMCPMC10524661
OpenAlexW4376114812

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.