Evidence map›Paper›PMID 37160974›Full record

ArticleNature communications2023

Highly host-linked viromes in the built environment possess habitat-dependent diversity and functions for potential virus-host coevolution.

Shicong Du, Xinzhao Tong, Alvin C K Lai, Chak K Chan, Christopher E Mason, Patrick K H Lee

Abstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Sulfonamide resistance geneMicrobiology spectrum · 2026
    Article
  5. Article
  6. Article
  7. The defensome of prokaryotes in aquifers.Nature communications · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. The indoors microbiome and human health.Nature reviews. Microbiology · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shicong DuSchool of Energy and Environment, City University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0002-6861-3319
Xinzhao TongSchool of Energy and Environment, City University of Hong Kong, Hong Kong SAR, China.
Alvin C K LaiSchool of Energy and Environment, City University of Hong Kong, Hong Kong SAR, China.
Chak K ChanSchool of Energy and Environment, City University of Hong Kong, Hong Kong SAR, China.
Christopher E MasonDepartment of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.ORCID 0000-0002-1850-1642
Patrick K H LeeSchool of Energy and Environment, City University of Hong Kong, Hong Kong SAR, China. patrick.kh.lee@cityu.edu.hk.ORCID 0000-0003-0911-5317

Funding

Supplement for MINI point-of-use deviceU01DA053941 · NIDA · UNIVERSITY OF MIAMI CORAL GABLES · PI MASON, CHRISTOPHER EDWARD, SCHURER, STEPHAN C · 2021 to 2022
$5.2M
Metagenomic profiling of urinary cell-free DNA to monitor urinary tract infection after kidney transplantationR01AI151059 · NIAID · CORNELL UNIVERSITY · PI DADHANIA, DARSHANA, DE VLAMINCK, IWIJN · 2020 to 2024
$3.4M
NIAID NIH HHS R01 AI151059NIDA NIH HHS U01 DA053941
6 · The paper itself

Abstract

Viruses in built environments (BEs) raise public health concerns, yet they are generally less studied than bacteria. To better understand viral dynamics in BEs, this study assesses viromes from 11 habitats across four types of BEs with low to high occupancy. The diversity, composition, metabolic functions, and lifestyles of the viromes are found to be habitat dependent. Caudoviricetes species are ubiquitous on surface habitats in the BEs, and some of them are distinct from those present in other environments. Antimicrobial resistance genes are identified in viruses inhabiting surfaces frequently touched by occupants and in viruses inhabiting occupants' skin. Diverse CRISPR/Cas immunity systems and anti-CRISPR proteins are found in bacterial hosts and viruses, respectively, consistent with the strongly coupled virus-host links. Evidence of viruses potentially aiding host adaptation in a specific-habitat manner is identified through a unique gene insertion. This work illustrates that virus-host interactions occur frequently in BEs and that viruses are integral members of BE microbiomes.

Indexed as

Alkanesulfonic AcidsMicrobiotaBuilt EnvironmentViromeAlkanesulfonic AcidsBES

Identifiers

PMID37160974
PMCPMC10169181

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.