Evidence map›Paper›PMID 37160596›Full record

Observational studyTechniques in coloproctology2023

Transanal irrigation in functional bowel disorders and LARS: short-term results from an Italian national study.

E Falletto, J Martellucci, P Rossitti, A Bondurri, G Zaffaroni, S Ascanelli, L Chimisso, A Lauretta, M Mirafiori, I Clementi and 11 more

Erratum issuedAbstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Techniques in coloproctology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 4 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 4 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Transanal irrigation: Bridging the gap in treatment for chronic constipation and/or faecal incontinence-A systematic review and management guidance.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025
    Pooled it
  3. Pooled it
  4. Guideline
  5. Article
  6. Transanal irrigation in clinical practice: a scoping review.International journal of colorectal disease · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors at 12 institutions in 1 country.

E FallettoDepartment of Surgical Sciences, Città Della Salute e Della Scienza, University of Torino, Turin, Italy. efalletto@cittadellasalute.to.it.ORCID http://orcid.org/0000-0001-6157-5236
J MartellucciUnit of Emergency Surgery, Careggi University Hospital, Florence, Italy.ORCID http://orcid.org/0000-0002-7437-9098
P RossittiGastroenterology and GI Endoscopy Unit, University Hospital of Udine, Udine, Italy.ORCID http://orcid.org/0000-0003-1611-2691
A BondurriDepartment of General Surgery, Department of Biomedical and Clinical Sciences, "Luigi Sacco", "Luigi Sacco" University Hospital, Milan, Italy.ORCID http://orcid.org/0000-0002-6521-5876
G ZaffaroniDepartment of General Surgery, Department of Biomedical and Clinical Sciences, "Luigi Sacco", "Luigi Sacco" University Hospital, Milan, Italy.ORCID http://orcid.org/0000-0002-1831-3107
S AscanelliDepartment of Morphology, Surgery and Experimental Medicine, General Surgery Unit, University of Ferrara, Ferrara, Italy.ORCID http://orcid.org/0000-0002-1423-8576
L ChimissoDepartment of Morphology, Surgery and Experimental Medicine, General Surgery Unit, University of Ferrara, Ferrara, Italy.ORCID http://orcid.org/0000-0002-4538-578X
A LaurettaDepartment of Surgical Oncology, Centro di Riferimento Oncologico di Aviano IRCCS, Aviano, Italy.ORCID http://orcid.org/0000-0002-1639-3908
M MirafioriDepartment of Surgical Oncology, Centro di Riferimento Oncologico di Aviano IRCCS, Aviano, Italy.ORCID http://orcid.org/0000-0001-8103-4162
I ClementiDepartment of Surgery "Pietro Valdoni", Policlinico Umberto I "Sapienza", University of Rome, Rome, Italy.ORCID http://orcid.org/0000-0002-2176-2085
V RipettiDepartment of Pelvic Floor Surgery and Proctology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
P LufarelliDepartment of Pelvic Floor Surgery and Proctology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.ORCID http://orcid.org/0000-0002-2503-8123
G CestaroGeneral Surgery Unit, Sant'Antonio Abate Hospital in Gallarate, ASST Valle Olona, Varese, Italy.ORCID http://orcid.org/0000-0002-9091-0731
C BottiniGeneral Surgery Unit, Sant'Antonio Abate Hospital in Gallarate, ASST Valle Olona, Varese, Italy.
M BelliniDepartment of Translational Sciences and New Technologies in Medicine and Surgery, Gastrointestinal Unit, University of Pisa, Pisa, Italy.ORCID http://orcid.org/0000-0002-6387-6443
C LambiaseDepartment of Translational Sciences and New Technologies in Medicine and Surgery, Gastrointestinal Unit, University of Pisa, Pisa, Italy.ORCID http://orcid.org/0000-0002-9565-5039
F Di CandidoColorectal Surgery Unit, AUSL Romagna, Ospedale per gli Infermi, Faenza, Italy.ORCID http://orcid.org/0000-0002-2284-4357
D ZattoniColorectal Surgery Unit, AUSL Romagna, Ospedale per gli Infermi, Faenza, Italy.ORCID http://orcid.org/0000-0001-7796-1262
S CornagliaGeneral Surgery Division, Koelliker Hospital, Turin, Italy.
P TonelloGeneral Surgery Division, Koelliker Hospital, Turin, Italy.
E ZucchiGastroenterology and GI Endoscopy Unit, University Hospital of Udine, Udine, Italy.ORCID http://orcid.org/0000-0003-2545-7587
Azienda Ospedaliera Sant’Antonio Abate di Gallarate · ITCampus Bio Medico University Hospital · ITCentro di Riferimento Oncologico · ITLuigi Sacco Hospital · ITOspedale Koelliker · ITOspedale per gli Infermi · ITUniversity of Ferrara · ITUniversity of Pisa · ITUniversity of Udine · ITAzienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITAzienda Ospedaliero-Universitaria Careggi · ITPoliclinico Umberto I · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the potential benefits associated with the short-term (6 months) treatment with transanal irrigation (TAI) in patients suffering from functional constipation (FC), functional fecal incontinence (FI), and low anterior resection syndrome (LARS).

methodsA multicenter observational study (12 centers; 369 patients) was conducted to assess the following primary and secondary objectives: to evaluate the level of satisfaction regarding bowel control and quality of life (QoL); to evaluate bowel symptoms severity and dropout frequency and reason. To this aim, validated questionnaires were provided to the patients at baseline (T0) and after 6 months of TAI treatment (T6) performed with the medical device Peristeen

resultsA 6-month treatment with TAI enabled a statistically significant (p < 0.05) improvement of QoL scores, satisfaction scores regarding bowel control, and severity indexes of disorder-related symptoms in patients suffering from FC, FI, and LARS. Globally, 8.0% of patients discontinued the treatment after 6 months as a result of occurrence of symptoms (2.4%) or other justifications (3.8%) such as personal reasons. None of the dropouts were due to treatment inefficacy.

conclusionResults of the present study suggest that short-term TAI treatment is beneficial for patients suffering from functional bowel disorders and LARS. Future analysis of prospective data will focus on the clinical outcomes associated with the long-term use (up to 24 months) of TAI when dealing with these types of medical conditions.

Indexed as

Irritable Bowel SyndromeRectal NeoplasmsHumansLow Anterior Resection SyndromePostoperative ComplicationsProspective StudiesQuality of LifeFunctional bowel disordersLARSTAITransanal irrigation

Identifiers

PMID37160596
OpenAlexW4366982615

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.