Trial reportIrish journal of medical science2023
Effect of aerobic exercise alone or combined with Mediterranean diet on dry eye in obese hypertensive elderly.
Trial report in Irish journal of medical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- EffectS of Lifestyle Interventions in Older PEople With Obesity (Effective SLOPE): a Systematic Review With Network Meta-Analyses.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Pooled it
- The effect of MIND diet on sleep status, mental health, and serum level of BDNF in overweight/obese diabetic women with insomnia: a randomized controlled trial.Scientific reports · 2025Trial
- Exercise and Nutrition in the Mental Health of the Older Adult Population: A Randomized Controlled Clinical Trial.Nutrients · 2024Trial
- Trial
- Erectile dysfunction and metabolic syndrome components in obese men with psoriasis: response to a 12-week randomized controlled lifestyle modification program (exercise with diet restriction).Irish journal of medical science · 2024Trial
- Beyond Glycemic Control: Ocular Effects of Glucagon-like Peptide-1 Receptor Agonists.Vision (Basel, Switzerland) · 2026Review
- Accelerometer-derived moderate-to-vigorous physical activity patterns and incident dry eye disease: a prospective UK Biobank cohort study.BMC public health · 2026Article
- Effects of six traditional Chinese mind-body exercises on obesity and cardiovascular risk factors in middle-aged and elderly hypertensive patients: a network Meta-Analysis of 49 RCTs.BMC cardiovascular disorders · 2025Article
- Management Strategies for Dry Eye Syndrome in Patients with Obesity-A Literature Review.Life (Basel, Switzerland) · 2025Review
- Effects of high dietary carbohydrate intake in patients with obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2024Article
- Physically Active Lifestyle Attenuates Impairments on Lung Function and Mechanics in Hypertensive Older Adults.Advances in respiratory medicine · 2024Article
- Obesity, body fat distribution and eye diseases.Eating and weight disorders : EWD · 2024Review
- Virtual reality technology improves the gait and balance function of the elderly: a meta-analysis of randomized controlled trials.Archives of medical science : AMS · 2024Review
- Effectiveness of Nurse-led Lifestyle Modification Intervention on Obesity Among Young Women in India.SAGE open nursingArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLifestyle modification is a newly recommended complementary treatment for dry eye (DE) disorder.
objectiveTo investigate the effect of a 6-month high-intensity interval aerobic exercise (HIIAE) (conducted 30 min, 3 times weekly) alone or combined with a caloric-restriction approach, the Mediterranean diet (MD), on DE parameters in obese hypertensive elderly. THE DESIGN, SETTINGS, PARTICIPANTS, AND
interventionThis is a randomized controlled trial included sixty obese hypertensive elderly with DE based on university-based hospital recruitment. Elderly were randomly assigned to the experimental group (n = 30 elderly received HIIAE plus MD) and control group (n = 30 elderly received only HIIAE). Besides anthropometry (abdominal circumference, body weight, and body mass index) and blood pressure (measured in systole and diastole), DE parameters (tear film break-up time, DE scoring system, ocular surface disability index questionnaire, Schirmer's test, and Oxford grading system) were evaluated.
resultsSignificant improvements in anthropometry, blood pressure, and DE parameters were higher in the experimental group than in the control group.
conclusionAging-related DE symptoms and signs can be prevented and/or treated with HIIAE alone or combined with MD in obese hypertensive elderly with DE disorder.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.