Evidence map›Paper›PMID 37160497›Full record

ArticleMycopathologia2023

Fungal Keratitis Caused by Talaromyces coalescens: A Case Report.

Daisuke Todokoro, Tomoko Miyakubo, Koichi Makimura, Takashi Tamura, Aya Komori, Hideo Akiyama

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Mycopathologia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Daisuke TodokoroDepartment of Ophthalmology, Gunma University Graduate School of Medicine, 3-39-15 Showa-machi, Maebashi-city, Gunma, 371-8511, Japan. dtodokor@gunma-u.ac.jp.
Tomoko MiyakuboDepartment of Ophthalmology, Gunma University Graduate School of Medicine, 3-39-15 Showa-machi, Maebashi-city, Gunma, 371-8511, Japan.
Koichi MakimuraTeikyo University Institute of Medical Mycology, 2-11-1 Koga, Itabashi-ku, Tokyo, 173-8605, Japan.
Takashi TamuraTeikyo University Institute of Medical Mycology, 2-11-1 Koga, Itabashi-ku, Tokyo, 173-8605, Japan.
Aya KomoriTeikyo University Institute of Medical Mycology, 2-11-1 Koga, Itabashi-ku, Tokyo, 173-8605, Japan.
Hideo AkiyamaDepartment of Ophthalmology, Gunma University Graduate School of Medicine, 3-39-15 Showa-machi, Maebashi-city, Gunma, 371-8511, Japan.
Gunma University · JPTeikyo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungal keratitis is a severe corneal infection, and the causative fungi include various rare fungal species. Fungal keratitis caused by Talaromyces species has yet to be reported, and there is no information about this fungus as a cause of keratitis. A 77-year-old man developed fungal keratitis while waiting for a donor cornea due to bullous keratopathy in his left eye. Fungal culture of a corneal scraping grew filamentous fungi, which were morphologically identified as Paecilomyces species. The corneal infection did not improve after topical administration of 1% voriconazole, and ribosomal DNA sequencing definitively verified the fungus to be Talaromyces coalescens. The lesion gradually improved after switching to topical 5% natamycin. Antifungal susceptibility tests determined the high minimum inhibitory concentrations of voriconazole to be > 8 μg/mL. This is the first report of Talaromyces fungal keratitis. Clinicians, especially those in ophthalmology, need to be aware of this rare fungus.

Indexed as

Corneal UlcerEye Infections, FungalKeratitisTalaromycesAgedAntifungal AgentsHumansMaleNatamycinVoriconazoleAntifungal AgentsNatamycinVoriconazoleFungal keratitisNatamycinTalaromyces coalescensVoriconazole

Identifiers

PMID37160497
PMCPMC10307905
OpenAlexW4376105979

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.