Evidence map›Paper›PMID 37160486›Full record

ArticleInternational urology and nephrology2023

Effect of stress hyperglycaemia on acute kidney injury in non-diabetic critically ill patients?

Perihan Ülger, Ebru Yildiz, Bartosz Tyczynski, Hajo Findeisen, Andreas Kribben, Onno E Janssen, Stefan Herget-Rosenthal

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Article in International urology and nephrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Perihan ÜlgerDepartment of Nephrology, University Duisburg-Essen, Essen, Germany.
Ebru YildizDepartment of Nephrology, University Duisburg-Essen, Essen, Germany.
Bartosz TyczynskiDepartment of Nephrology, University Duisburg-Essen, Essen, Germany.
Hajo FindeisenDepartment of Medicine, Rotes Kreuz Krankenhaus, St. Pauli Deich 24, 28199, Bremen, Germany.
Andreas KribbenDepartment of Nephrology, University Duisburg-Essen, Essen, Germany.
Onno E JanssenEndokrinologikum, and Asklepios Medical School, Hamburg, Germany.ORCID http://orcid.org/0000-0003-2614-4160
Stefan Herget-RosenthalDepartment of Nephrology, University Duisburg-Essen, Essen, Germany. herget-rosenthal.s@roteskreuzkrankenhaus.de.ORCID http://orcid.org/0000-0001-9217-5980
University of Duisburg-Essen · DEKrankenhaus vom Roten Kreuz · DESemmelweis University · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStress hyperglycaemia (SH) and acute kidney injury (AKI) occur frequently in critically ill patients, and particularly non-diabetics are associated with adverse outcome. Data is scarce on the effect of SH on AKI. We assessed whether SH (i) preceded AKI, (ii) was a risk factor of subsequent AKI, and (iii) how SH and tubular injury interacted in AKI development in critically ill, non-diabetics.

methodsCase-control study of 82 patients each with and without SH matched by propensity score for multiple demographic characteristics. AKI was defined by KDIGO criteria, SH either as blood glucose (BG) > 140 mg/dl (BG

resultsIn AKI, SH rates were frequent using all 3 definitions applied, but highest when BG

conclusionsSH is frequent in critically ill, non-diabetics with AKI. SH was identified as an independent risk factor of AKI. Higher BG combined with tubular injury may potentiate their adverse effects on AKI.

Indexed as

Acute Kidney InjuryHyperglycemiaBiomarkersCase-Control StudiesCritical IllnessCystatin CHumansLipocalin-2BiomarkersCystatin CLipocalin-2Acute kidney injuryCritical illnessCystatin CGlucotoxicityNeutrophil gelatinase-associated lipocalinStress hyperglycaemia

Identifiers

PMID37160486
OpenAlexW4376108636

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.