ArticleCerebral cortex (New York, N.Y. : 1991)2023
Hippocampal theta activity during encoding promotes subsequent associative memory in humans.
Article in Cerebral cortex (New York, N.Y. : 1991), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Task-Specific Personalized Theta tACS Modulates Theta Dynamics in Associative Memory.Brain and behavior · 2026Trial
- Article
- Article
- High-caloric intake rescues early symptomatic AD-induced hippocampal neurovascular coupling deficits.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Theta-phase locking of single neurons during human spatial memory.Nature communications · 2025Article
- Neural Dynamics of Visual Stream Interactions During Memory-Guided Actions Investigated by Intracranial EEG.Neuroscience bulletin · 2025Article
- Neocortical and Hippocampal Theta Oscillations Track Audiovisual Integration and Replay of Speech Memories.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- EEG focal delta slowing in focal epilepsy - A didactic review.Clinical neurophysiology practice · 2025Review
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Hippocampal theta oscillations have been implicated in associative memory in humans. However, findings from electrophysiological studies using scalp electroencephalography or magnetoencephalography, and those using intracranial electroencephalography are mixed. Here we asked 10 pre-surgical epilepsy patients undergoing intracranial electroencephalography recording, along with 21 participants undergoing magnetoencephalography recordings, to perform an associative memory task, and examined whether hippocampal theta activity during encoding was predictive of subsequent associative memory performance. Across the intracranial electroencephalography and magnetoencephalography studies, we observed that theta power in the hippocampus increased during encoding, and that this increase differed as a function of subsequent memory, with greater theta activity for pairs that were successfully retrieved in their entirety compared with those that were not remembered. This helps to clarify the role of theta oscillations in associative memory formation in humans, and further, demonstrates that findings in epilepsy patients undergoing intracranial electroencephalography recordings can be extended to healthy participants undergoing magnetoencephalography recordings.
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