Evidence map›Paper›PMID 37159792›Full record

ArticleCureus2023

Bleeding Diathesis as the Initial Presentation of Chronic Myeloid Leukemia: A Case Series.

Farjah H AlGahtani, Leena Alshaman, Ghada ElGohary, Aamer Aleem, Fatmah S AlQahtany

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review of Bleeding as Initial Presentation in Patients with Chronic Myeloid Leukemia.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Farjah H AlGahtaniDivision of Hematology/Oncology, Department of Medicine, College of Medicine, King Saud University, King Saud University Medical City, Riyadh, SAU.
Leena AlshamanDivision of Hematology/Oncology, Department of Medicine, College of Medicine, King Saud University, King Saud University Medical City, Riyadh, SAU.
Ghada ElGoharyHematology and Oncology, Division of Hematology/oncology, College of Medicine, King Saud Medical City King Saud University, Riyadh, Saudi Arabia, and Departement of Adult Hematology/internal Medicine, Faculty of Medicine, Ain Shams University, Cairo, Egypt, Cairo, EGY.
Aamer AleemDivision of Hematology/Oncology, Department of Medicine, College of Medicine, King Saud University, King Saud University Medical City, Riyadh, SAU.
Fatmah S AlQahtanyHematopathology Unit, Department of Pathology, College of Medicine, King Saud University, King Saud University Medical City, Riyadh, SAU.
Ain Shams University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic myelogenous leukemia, or CML, is another name for chronic myeloid leukemia (CML), a cancer type that starts in certain bone marrow blood-forming cells. The primary initiator of granulocytic proliferation in CML, a myeloproliferative malignancy, is the BCR-ABL1 fusion protein or Philadelphia chromosome. CML is classified into three stages: chronic, accelerated, and blast. It has been widely recognized that the likelihood of developing CML varies by gender, geography, and age. In the chronic phase of CML (CML-CP), bleeding is a rare sign since the thrombocyte and coagulation functions are still adequate. Uncertainties exist regarding the CML bleeding mechanism. We report four cases of CML-CP in adult patients. The majority of these patients had CML and had idiopathic spontaneous bleeding in multiple locations.

Indexed as

bcr-ablchronic myeloid leukemiachronic phasephiladelphia chromosometyrosine kinase inhibitor (tki)

Identifiers

PMID37159792
PMCPMC10163831
OpenAlexW4362666460

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.