Evidence map›Paper›PMID 37159701›Full record

ArticleHeliyon2023

Physicochemical characterization and cancer cell antiproliferative effect of silver-doped magnesia nanoparticles.

Mohamed Qasim Al-Fahdawi, Ahmed Faris Aldoghachi, Fatah H Alhassan, Faris A J Al-Doghachi, Hussah Abdullah Alshwyeh, Abdullah Rasedee, Sulaiman Mohammed Alnasser, Mothanna Sadiq Al-Qubaisi, Wisam Nabeel Ibrahim

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 4 countries.

Mohamed Qasim Al-FahdawiInstitute of Bioscience, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia.
Ahmed Faris AldoghachiFaculty of Medicine and Health Sciences, University Putra Malaysia, UPM, Serdang, 43300, Malaysia.
Fatah H AlhassanDepartment of Applied Chemistry and Technology, College of Science and Arts, Alkamel University of Jeddah, Jeddah, 21589, Saudi Arabia.
Faris A J Al-DoghachiDepartment of Chemistry, Faculty of Science, University of Basra, Basra, Iraq.
Hussah Abdullah AlshwyehDepartment of Biology, College of Science, Imam Abdulrahman Bin Faisal University, Dammam, 31441, Saudi Arabia.
Abdullah RasedeeInstitute of Bioscience, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia.
Sulaiman Mohammed AlnasserDepartment of Pharmacology and Toxicology, Unaizah College of Pharmacy, Qassim University, Saudi Arabia.
Mothanna Sadiq Al-QubaisiInstitute of Bioscience, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia.
Wisam Nabeel IbrahimDepartment of Biomedical Science, College of Health Sciences, QU Health, Qatar University, Doha, Qatar.
Universiti Putra Malaysia · MYImam Abdulrahman Bin Faisal University · SAQassim University · SAQatar University · QAUniversity of Basrah · IQUniversity of Jeddah · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Silver-doped magnesia nanoparticles (Ag/MgO) were synthesized using the precipitation method and characterized by various techniques such as X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), thermal gravimetric analysis (TGA), Brunner-Emmett-Teller (BET) surface area measurements, and dispersive X-ray spectroscopy (EDX). The morphology of Ag/MgO nanoparticles was determined by transmission and scanning electron microscopy, which revealed cuboidal shaped nanoparticles with sizes ranging from 31 to 68 nm and an average size of 43.5 ± 10.6 nm. The anticancer effects of Ag/MgO nanoparticles were evaluated on human colorectal (HT29) and lung adenocarcinoma (A549) cell lines, and their caspase-3, -8, and -9 activities, as well as Bcl-2, Bax, p53, cytochrome C protein expressions were estimated. Ag/MgO nanoparticles showed selective toxicity towards HT29 and A549 cells while remaining relatively innocuous towards the normal human colorectal, CCD-18Co, and lung, MRC-5 cells. The IC

Indexed as

A549 cellAg/MgO nanoparticlesAntiproliferativeApoptosisHT29 cell

Identifiers

PMID37159701
PMCPMC10163622
OpenAlexW4366132782

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.