Evidence map›Paper›PMID 37159672›Full record

ArticleCell reports methods2023

Jelena A Juras, Madison B Webb, Lyndsay E A Young, Kia H Markussen, Tara R Hawkinson, Michael D Buoncristiani, Kayli E Bolton, Peyton T Coburn, Meredith I Williams, Lisa P Y Sun and 7 more

Open access · goldAbstract read
In one paragraph

Article in Cell reports methods, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Setting standards for brain collection procedures in metabolomic studies.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Review
  2. Article
  3. Article
  4. Spatial Molecular Imaging of the Glycome Using Mass Spectrometry.Journal of visualized experiments : JoVE · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Brain communications · 2024
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Jelena A JurasDepartment of Neuroscience, University of Kentucky, College of Medicine, Lexington, KY 40536, USA.
Madison B WebbDepartment of Molecular and Cellular Biochemistry, University of Kentucky, College of Medicine, Lexington, KY 40536, USA.
Lyndsay E A YoungDepartment of Molecular and Cellular Biochemistry, University of Kentucky, College of Medicine, Lexington, KY 40536, USA.
Kia H MarkussenDepartment of Molecular and Cellular Biochemistry, University of Kentucky, College of Medicine, Lexington, KY 40536, USA.
Tara R HawkinsonDepartment of Neuroscience, University of Kentucky, College of Medicine, Lexington, KY 40536, USA.
Michael D BuoncristianiDepartment of Neuroscience, University of Kentucky, College of Medicine, Lexington, KY 40536, USA.
Kayli E BoltonDepartment of Molecular and Cellular Biochemistry, University of Kentucky, College of Medicine, Lexington, KY 40536, USA.
Peyton T CoburnDepartment of Molecular and Cellular Biochemistry, University of Kentucky, College of Medicine, Lexington, KY 40536, USA.
Meredith I WilliamsDepartment of Molecular and Cellular Biochemistry, University of Kentucky, College of Medicine, Lexington, KY 40536, USA.
Lisa P Y SunDepartment of Neuroscience, University of Kentucky, College of Medicine, Lexington, KY 40536, USA.
William C SandersDepartment of Molecular and Cellular Biochemistry, University of Kentucky, College of Medicine, Lexington, KY 40536, USA.
Ronald C BruntzDepartment of Molecular and Cellular Biochemistry, University of Kentucky, College of Medicine, Lexington, KY 40536, USA.
Lindsey R ConroyDepartment of Neuroscience, University of Kentucky, College of Medicine, Lexington, KY 40536, USA.
Chi WangMarkey Cancer Center, University of Kentucky, Lexington, KY 40536, USA.
Matthew S GentryDepartment of Molecular and Cellular Biochemistry, University of Kentucky, College of Medicine, Lexington, KY 40536, USA.
Bret N SmithDepartment of Neuroscience, University of Kentucky, College of Medicine, Lexington, KY 40536, USA.
Ramon C SunDepartment of Neuroscience, University of Kentucky, College of Medicine, Lexington, KY 40536, USA.
University of Kentucky · US

Funding

University of Kentucky Markey Cancer Center Support Grant ECIA SupplementP30CA177558 · NCI · UNIVERSITY OF KENTUCKY · PI Jennifer F Rogers · 2013 to 2026
$38.3M
Suppressing glycogen storage with small molecule inhibitors as a therapeutic approach to Lafora DiseaseP01NS097197 · NINDS · UNIVERSITY OF KENTUCKY · PI GAO, TIANYAN · 2016 to 2021
$9.0M
Brain Glycogen-Metabolism,Mechanisms, and Therapeutic PotentialR35NS116824 · NINDS · UNIVERSITY OF KENTUCKY · PI Matthew S. Gentry · 2020 to 2026
$8.2M
Appalachian Career Training in Oncology (ACTION) ProgramR25CA221765 · NCI · UNIVERSITY OF KENTUCKY · PI Nathan Lane Vanderford · 2018 to 2026
$3.7M
Interdisciplinary Research Training in Cancer BiologyT32CA165990 · NCI · UNIVERSITY OF KENTUCKY · PI Bernard Mark Evers, KATHLEEN L. O'CONNOR · 2013 to 2026
$3.2M
Aberrant Glycogen in Lung Adenocarcinoma TumorigenesisR01CA266004 · NCI · UNIVERSITY OF KENTUCKY · PI Matthew S. Gentry, Ramon C. Sun · 2022 to 2026
$2.6M
Contribution of adult neurogenesis to epileptogenesis and recovery after TBIR01NS092552 · NINDS · UNIVERSITY OF KENTUCKY · PI SMITH, BRET N · 2018 to 2022
$2.1M
Diabetes, glucose metabolism, and neuroplasticity in the vagal complexR01DK122811 · NIDDK · UNIVERSITY OF KENTUCKY · PI SMITH, BRET N · 2020 to 2023
$1.9M
Aberrant Glycogen Modulates Cerebral Glucose Metabolism in Aging and Alzheimer's DiseaseR01AG066653 · NIA · UNIVERSITY OF KENTUCKY · PI SUN, RAMON C. · 2020 to 2024
$1.9M
Aberrant Glycogen Modulates Metabolism in Ewing’s SarcomaF99CA264165 · NCI · UNIVERSITY OF KENTUCKY · PI YOUNG, LYNDSAY E A · 2021 to 2022
$79k
NCI NIH HHS F99 CA264165NCI NIH HHS P30 CA177558NCI NIH HHS R01 CA266004NCI NIH HHS R25 CA221765NCI NIH HHS T32 CA165990NIA NIH HHS R01 AG066653NIDDK NIH HHS R01 DK122811NINDS NIH HHS P01 NS097197NINDS NIH HHS R01 NS092552NINDS NIH HHS R35 NS116824
6 · The paper itself

Abstract

Brain glucose metabolism is highly heterogeneous among brain regions and continues postmortem. In particular, we demonstrate exhaustion of glycogen and glucose and an increase in lactate production during conventional rapid brain resection and preservation by liquid nitrogen. In contrast, we show that these postmortem changes are not observed with simultaneous animal sacrifice and

Indexed as

BrainMicrowavesAnimalsGlucoseGlycogenMetabolomeMiceGlucoseGlycogenbrain metabolismisotope tracingmicrowave fixationregional metabolismtype 1 diabetes

Identifiers

PMID37159672
PMCPMC10163000
OpenAlexW4366267810

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.