Evidence map›Paper›PMID 37159669›Full record

ArticleCell reports methods2023

Systematic comparison of multi-omics survival models reveals a widespread lack of noise resistance.

David Wissel, Daniel Rowson, Valentina Boeva

Abstract read
In one paragraph

Article in Cell reports methods, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

David WisselETH Zurich, Department of Computer Science, Zurich, Switzerland.
Daniel RowsonETH Zurich, Department of Computer Science, Zurich, Switzerland.
Valentina BoevaETH Zurich, Department of Computer Science, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As observed in several previous studies, integrating more molecular modalities in multi-omics cancer survival models may not always improve model accuracy. In this study, we compared eight deep learning and four statistical integration techniques for survival prediction on 17 multi-omics datasets, examining model performance in terms of overall accuracy and noise resistance. We found that one deep learning method, mean late fusion, and two statistical methods,

Indexed as

MultiomicsCalibrationcancerdeep learning modelsmulti-modal integrationmulti-omicsnoise resistancestatistical modelssurvival analysis

Identifiers

PMID37159669
PMCPMC10162996

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.