Evidence map›Paper›PMID 37159620›Full record

ArticleBMJ medicine2023

Quantifying the impact of unmeasured confounding in observational studies with the E value.

Tobias Gaster, Christine Marie Eggertsen, Henrik Støvring, Vera Ehrenstein, Irene Petersen

Abstract read
In one paragraph

Article in BMJ medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  17. Inverse Association Between Betel Quid Use and Diabetes in Rural Bangladesh.American journal of human biology : the official journal of the Human Biology Council · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tobias Gaster *Aarhus University, Aarhus, Denmark.
Christine Marie Eggertsen *Aarhus University, Aarhus, Denmark.
Henrik StøvringSteno Diabetes Centre Aarhus, Aarhus, Denmark.ORCID 0000-0002-5821-2351
Vera EhrensteinDepartment of Clinical Epidemiology, Aarhus University and Aarhus University Hospital, Aarhus, Denmark.ORCID 0000-0002-3415-3254
Irene PetersenDepartment of Clinical Epidemiology, Aarhus University and Aarhus University Hospital, Aarhus, Denmark.ORCID 0000-0002-0037-7524

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The E value method deals with unmeasured confounding, a key source of bias in observational studies. The E value method is described and its use is shown in a worked example of a meta-analysis examining the association between the use of antidepressants in pregnancy and the risk of miscarriage.

Indexed as

EpidemiologyObstetricsPregnancy complications

Identifiers

PMID37159620
PMCPMC10163534

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.