Evidence map›Paper›PMID 37159468›Full record

ArticlePloS one2023

Artificially-generated consolidations and balanced augmentation increase performance of U-net for lung parenchyma segmentation on MR images.

Cristian Crisosto, Andreas Voskrebenzev, Marcel Gutberlet, Filip Klimeš, Till F Kaireit, Gesa Pöhler, Tawfik Moher, Lea Behrendt, Robin Müller, Maximilian Zubke and 2 more

Abstract read
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Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Cristian CrisostoInstitute for Diagnostic and Interventional Radiology, Hannover Medical School (MHH), Hannover, Germany.ORCID 0000-0002-3006-0229
Andreas VoskrebenzevInstitute for Diagnostic and Interventional Radiology, Hannover Medical School (MHH), Hannover, Germany.
Marcel GutberletInstitute for Diagnostic and Interventional Radiology, Hannover Medical School (MHH), Hannover, Germany.
Filip KlimešInstitute for Diagnostic and Interventional Radiology, Hannover Medical School (MHH), Hannover, Germany.ORCID 0000-0003-2715-0757
Till F KaireitInstitute for Diagnostic and Interventional Radiology, Hannover Medical School (MHH), Hannover, Germany.
Gesa PöhlerInstitute for Diagnostic and Interventional Radiology, Hannover Medical School (MHH), Hannover, Germany.
Tawfik MoherInstitute for Diagnostic and Interventional Radiology, Hannover Medical School (MHH), Hannover, Germany.ORCID 0000-0002-0779-0688
Lea BehrendtInstitute for Diagnostic and Interventional Radiology, Hannover Medical School (MHH), Hannover, Germany.
Robin MüllerInstitute for Diagnostic and Interventional Radiology, Hannover Medical School (MHH), Hannover, Germany.ORCID 0000-0002-2137-7355
Maximilian ZubkeInstitute for Diagnostic and Interventional Radiology, Hannover Medical School (MHH), Hannover, Germany.
Frank WackerInstitute for Diagnostic and Interventional Radiology, Hannover Medical School (MHH), Hannover, Germany.
Jens Vogel-ClaussenInstitute for Diagnostic and Interventional Radiology, Hannover Medical School (MHH), Hannover, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo improve automated lung segmentation on 2D lung MR images using balanced augmentation and artificially-generated consolidations for training of a convolutional neural network (CNN). MATERIALS AND

methodsFrom 233 healthy volunteers and 100 patients, 1891 coronal MR images were acquired. Of these, 1666 images without consolidations were used to build a binary semantic CNN for lung segmentation and 225 images (187 without consolidations, 38 with consolidations) were used for testing. To increase CNN performance of segmenting lung parenchyma with consolidations, balanced augmentation was performed and artificially-generated consolidations were added to all training images. The proposed CNN (CNNBal/Cons) was compared to two other CNNs: CNNUnbal/NoCons-without balanced augmentation and artificially-generated consolidations and CNNBal/NoCons-with balanced augmentation but without artificially-generated consolidations. Segmentation results were assessed using Sørensen-Dice coefficient (SDC) and Hausdorff distance coefficient.

resultsRegarding the 187 MR test images without consolidations, the mean SDC of CNNUnbal/NoCons (92.1 ± 6% (mean ± standard deviation)) was significantly lower compared to CNNBal/NoCons (94.0 ± 5.3%, P = 0.0013) and CNNBal/Cons (94.3 ± 4.1%, P = 0.0001). No significant difference was found between SDC of CNNBal/Cons and CNNBal/NoCons (P = 0.54). For the 38 MR test images with consolidations, SDC of CNNUnbal/NoCons (89.0 ± 7.1%) was not significantly different compared to CNNBal/NoCons (90.2 ± 9.4%, P = 0.53). SDC of CNNBal/Cons (94.3 ± 3.7%) was significantly higher compared to CNNBal/NoCons (P = 0.0146) and CNNUnbal/NoCons (P = 0.001).

conclusionsExpanding training datasets via balanced augmentation and artificially-generated consolidations improved the accuracy of CNNBal/Cons, especially in datasets with parenchymal consolidations. This is an important step towards a robust automated postprocessing of lung MRI datasets in clinical routine.

Indexed as

Neural Networks, ComputerSemantic WebHealthy VolunteersHumansLungThorax

Identifiers

PMID37159468
PMCPMC10168553

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.