SynthesisResearch in gerontological nursing
Loneliness and Functional Decline in Aging: A Systematic Review.
Synthesis in Research in gerontological nursing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- From verbal fluency to naturalistic speech: a scoping review of language correlates of loneliness and social isolation in older adults.Frontiers in aging neuroscience · 2026Pooled it
- Loneliness trajectories surrounding mobility loss: the role of disability duration.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026Article
- Treatment of Gender in Research on Intervention Programs Targeting Social Isolation and Loneliness Among Older Adults: Scoping Review.Interactive journal of medical research · 2026Review
- The moderating effect of age on loneliness and subjective remaining life expectancy among Chinese adults.Frontiers in public health · 2026Article
- Exploratory descriptive cross-sectional study on loneliness and participation in leisure activities among non-institutionalized older adults.Frontiers in public health · 2026Article
- Loneliness and cognitive function among Chinese older adults: multiple mediating effects of activities of daily living and anxiety.Frontiers in public health · 2026Article
- Article
- Social wellbeing in older breast cancer survivors taking adjuvant endocrine therapy: impacts of self-efficacy for symptom management and pain.Frontiers in aging · 2026Article
- Cross-Cultural Adaptation and Validation of the Beck Depression Inventory (BDI-II) in the Community Otomi of the Mezquital Valley, Mexico.Healthcare (Basel, Switzerland) · 2025Article
- Mapping the factors of loneliness in older adults: the role of employment and work activity - a scoping review.International journal of occupational medicine and environmental health · 2025Article
- Association between loneliness and self-care in elderly individuals with chronic kidney disease: a structural equation modeling approach.BMC public health · 2025Article
- The Intersection of Socioeconomic and Environmental Factors in Aging: Insights from a Narrative Review.International journal of environmental research and public health · 2025Review
- Behavioral Markers in Older Adults During COVID-19 Confinement: Secondary Analysis of In-Home Sensor Data.JMIR mHealth and uHealth · 2025Article
- Personality traits and loneliness: An ecological momentary assessment study with self and partner ratings.Journal of research in personality · 2025Article
- Loneliness and functional limitations shaping one another: evidence from the Health and Retirement Study.Aging & mental health · 2025Article
- Personality traits and social frailty in older adults: exploring the mediating effect of perceived loneliness.Frontiers in public health · 2025Observational
- Social isolation, loneliness, and functional disability in Chinese older women and men: a longitudinal cross-lag analysis.BMC psychology · 2024Article
- The Role of Functional Deficits, Depression, and Cognitive Symptoms in the Perceived Loneliness of Older Adults in Mexico City.International journal of environmental research and public health · 2024Article
- Difference-Making Pathways to Frailty Through Social Factors: A Configurational Analysis.The Gerontologist · 2024Article
- Loneliness Predicts Progression of Frailty in Married and Widowed, but Not Unmarried Community Dwelling Older Adults.The Journal of frailty & aging · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Loneliness is prevalent in adults aged ≥65 years in the United States and is associated with functional decline. The purpose of the current review was to synthesize evidence on the relationship between loneliness and functional decline using Roy's Adaptation Model as a theoretical framework. A comprehensive review of PubMed, Medline, and Embase databases was performed. Inclusion criteria were samples including adults primarily aged >60 years, peer-reviewed, published in the English language, and included a measure for loneliness and function. A total of 47 studies were analyzed. Most studies examined correlates, risk factors, and predictors of loneliness, rather than the relationship between loneliness and function. Evidence suggests there is bidirectionality in the relationship between loneliness and functional decline. Loneliness is associated with functional decline in aging via multiple possible pathways. Further studies are needed to determine causality and biological mechanisms underlying the relationship. [
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.