Evidence map›Paper›PMID 37158877›Full record

ArticleBMC microbiology2023

Characterization of oral bacterial and fungal microbiome in recovered COVID-19 patients.

Nana Wei, Guangqi Zhu, Tingxiao Zhao, Yan Wang, Haifei Lou, Haoxuan Li, Zhejuan Yang, Zheen Zhang, Qiujing Wang, Mingfang Han and 2 more

Abstract read
In one paragraph

Article in BMC microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Observational
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nana Wei *Key Laboratory of Adolescent Health Assessment and Exercise Intervention of Ministry of Education, East China Normal University, Shanghai, 200241, China.
Guangqi Zhu *Department of Infectious Disease, Zhoushan Hospital, Wenzhou Medical University, Zhoushan, 316021, China.
Tingxiao ZhaoDepartment of Infectious Disease, Zhejiang University Zhoushan Hospital, Zhoushan, 316021, China.
Yan WangDepartment of Infectious Disease, Zhoushan Hospital, Wenzhou Medical University, Zhoushan, 316021, China.
Haifei LouDepartment of Infectious Disease, Zhoushan Hospital, Wenzhou Medical University, Zhoushan, 316021, China.
Haoxuan LiWenzhou-Kean University, Wenzhou, 325060, China.
Zhejuan YangDepartment of Infectious Disease, Zhoushan Hospital, Wenzhou Medical University, Zhoushan, 316021, China.
Zheen ZhangDepartment of Infectious Disease, Zhoushan Hospital, Wenzhou Medical University, Zhoushan, 316021, China.
Qiujing WangDepartment of Infectious Disease, Zhoushan Hospital, Wenzhou Medical University, Zhoushan, 316021, China.
Mingfang HanDepartment of Infectious Disease, Zhoushan Hospital, Wenzhou Medical University, Zhoushan, 316021, China.
Zhibing LinShanghai Key Laboratory of Veterinary Biotechnology, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, 200240, China. mdzhibing@163.com.
Shibo LiDepartment of Infectious Disease, Zhoushan Hospital, Wenzhou Medical University, Zhoushan, 316021, China. lsb0398@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19 has emerged as a global pandemic, challenging the world's economic and health systems. Human oral microbiota comprises the second largest microbial community after the gut microbiota and is closely related to respiratory tract infections; however, oral microbiomes of patients who have recovered from COVID-19 have not yet been thoroughly studied. Herein, we compared the oral bacterial and fungal microbiota after clearance of SARS-CoV-2 in 23 COVID-19 recovered patients to those of 29 healthy individuals. Our results showed that both bacterial and fungal diversity were nearly normalized in recovered patients. The relative abundance of some specific bacteria and fungi, primarily opportunistic pathogens, decreased in recovered patients (RPs), while the abundance of butyrate-producing organisms increased in these patients. Moreover, these differences were still present for some organisms at 12 months after recovery, indicating the need for long-term monitoring of COVID-19 patients after virus clearance.

Indexed as

COVID-19MicrobiotaMycobiomeBacteriaHumansSARS-CoV-2COVID-19Oral bacteriaOral fungiRecovered patientsVirus clearance

Identifiers

PMID37158877
PMCPMC10166687

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.