Evidence map›Paper›PMID 37158618›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2023

Healthcare Utilization After Respiratory Tuberculosis: A Controlled Interrupted Time Series Analysis.

Kamila Romanowski, Michael R Law, Mohammad Ehsanul Karim, Jonathon R Campbell, Md Belal Hossain, Mark Gilbert, Victoria J Cook, James C Johnston

Open access · greenAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Mycobacterium tuberculosis reinforces M2 polarization of macrophages by activating glutamine metabolism.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
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  13. Perspectives from the 2IJTLD open · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Kamila RomanowskiProvincial Tuberculosis Services, British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada.
Michael R LawCentre for Health Services and Policy Research, The University of British Columbia, Vancouver, British Columbia, Canada.
Mohammad Ehsanul KarimSchool of Population and Public Health, Faculty of Medicine, The University of British Columbia, Vancouver, British Columbia, Canada.
Jonathon R CampbellRespiratory Epidemiology and Clinical Research Unit, Centre for Outcomes Research & Evaluation, Research Institute of the McGill University Health Centre, Montreal, Canada.
Md Belal HossainSchool of Population and Public Health, Faculty of Medicine, The University of British Columbia, Vancouver, British Columbia, Canada.
Mark GilbertSchool of Population and Public Health, Faculty of Medicine, The University of British Columbia, Vancouver, British Columbia, Canada.
Victoria J CookProvincial Tuberculosis Services, British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada.
James C JohnstonProvincial Tuberculosis Services, British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada.
BC Centre for Disease Control · CAUniversity of British Columbia · CACentre for Advancing Health Outcomes · CAMcGill University Health Centre · CA

Funding

CIHR PJT-153213
6 · The paper itself

Abstract

backgroundDespite data suggesting elevated morbidity and mortality among people who have survived tuberculosis disease, the impact of respiratory tuberculosis on healthcare utilization in the years following diagnosis and treatment remains unclear.

methodsUsing linked health administrative data from British Columbia, Canada, we identified foreign-born individuals treated for respiratory tuberculosis between 1990 and 2019. We matched each person with up to four people without a tuberculosis diagnosis from the same source cohort using propensity score matching. Then, using a controlled interrupted time series analysis, we measured outpatient physician encounters and inpatient hospital admissions in the 5 years following respiratory tuberculosis diagnosis and treatment.

resultsWe matched 1216 individuals treated for respiratory tuberculosis to 4864 non-tuberculosis controls. Immediately following the tuberculosis diagnostic and treatment period, the monthly rate of outpatient encounters in the tuberculosis group was 34.0% (95% confidence interval [CI]: 30.7%, 37.2%) higher than expected, and this trend was sustained for the duration of the post-tuberculosis period. The excess utilization represented an additional 12.2 (95% CI: 10.6, 14.9) outpatient encounters per person over the post-tuberculosis period, with respiratory morbidity a large contributor to the excess healthcare utilization. Results were similar for hospital admissions, with an additional 0.4 (95% CI: .3, .5) hospital admissions per person over the post-tuberculosis period.

conclusionsRespiratory tuberculosis appears to have long-term impacts on healthcare utilization beyond treatment. These findings underscore the need for screening, assessment, and treatment of post-tuberculosis sequelae, as it may provide an opportunity to improve health and reduce resource use.

Indexed as

TuberculosisTuberculosis, PulmonaryBritish ColumbiaDelivery of Health CareHumansInterrupted Time Series AnalysisPatient Acceptance of Health Careepidemiologyhealthcare utilizationpost-tuberculosis

Identifiers

PMID37158618
PMCPMC10506780
OpenAlexW4375955355

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.