Evidence map›Paper›PMID 37158581›Full record

ArticleInterdisciplinary cardiovascular and thoracic surgery2023

Ventriculo-arterial coupling for predicting cardiac index increase in infants after heart surgery.

Wenjuan Li, Yongxuan Peng, Zhihao Li, Jihong Huang

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Interdisciplinary cardiovascular and thoracic surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Milrinone, we all like you ….Interdisciplinary cardiovascular and thoracic surgery · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Wenjuan LiDepartment of Pediatric Cardiology, Xinhua Hospital, Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yongxuan PengDepartment of Pediatric Cardiology, Xinhua Hospital, Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhihao LiDepartment of Pediatric Cardiovascular and Thoracic Surgery, Shanghai Children's Medical Center, Medical School of Shanghai Jiaotong University, Shanghai, China.
Jihong HuangDepartment of Pediatric Cardiology, Xinhua Hospital, Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID 0000-0001-7925-7244
Shanghai Jiao Tong University · CNShanghai Children's Medical Center · CN

Funding

Shanghai Municipal Health Commission Clinical Research 201840347Xinhua Hospital&Shanghai Jiao Tong University
6 · The paper itself

Abstract

objectivesThe aim of this study was to test the ability of ventriculo-arterial coupling (VAC) to predict cardiac index (CI) response after milrinone infusion.

methodsThis was a retrospective, observational study. We measured arterial blood pressure and echocardiography-derived variables, including CI, systemic vascular resistance index, arterial elastance (Ea) and end-systolic ventricular elastance before and after 18-24 h of milrinone infusion. VAC was calculated as the ratio of Ea to end-systolic elastance. Infants with over 15% increase in the CI were defined as CI responders. Logistical regression was used to evaluate predictors of CI responders.

resultsWe enrolled 92 infants who underwent cardiac surgery and received milrinone infusion, of whom 45 infants were CI responders. High VAC (odds ratio = 5.534, 95% confidence interval 2.339-13.090) and high Ea (odds ratio = 3.035, 95% confidence interval 1.459-6.310) were independently associated with cardiac index responders. Pre-milrinone VAC predicted CI responsiveness with a cut-off value of 1.12 (area under the curve = 0.900, 95% confidence interval 0.819-0.953, P < 0.0001). Furthermore, we observed a decrease in the infant's VAC, Ea and systemic vascular resistance index after milrinone infusion.

conclusionsIn infants with congenital heart disease after surgery, a pre-milrinone VAC >1.12 can predict the increase in the CI following milrinone infusion.

Indexed as

Cardiac intensive careCongenital heart surgeryMilrinonePaediatricVentriculo-arterial coupling

Identifiers

PMID37158581
PMCPMC10497444
OpenAlexW4375954877

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.