Evidence map›Paper›PMID 37158063›Full record

ArticleJournal of the American Heart Association2023

Racial and Ethnic Differences in Cardiac Surveillance Evaluation of Patients Treated With Anthracycline-Based Chemotherapy.

David L DeRemer, Nam K Nguyen, Avirup Guha, Faraz S Ahmad, Rhonda M Cooper-DeHoff, Carl J Pepine, Michael G Fradley, Yan Gong

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Research summary of poster presentations at the 2023 Florida cardio-oncology symposium.American heart journal plus : cardiology research and practice · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

David L DeRemerDepartment of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, College of Pharmacy University of Florida Gainesville FL USA.ORCID 0000-0002-2207-9552
Nam K NguyenDepartment of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, College of Pharmacy University of Florida Gainesville FL USA.ORCID 0000-0003-3036-4748
Avirup GuhaCardio-Oncology Program, Georgia Cancer Center Medical College of Georgia at Augusta, University Augusta GA USA.ORCID 0000-0003-0253-1174
Faraz S AhmadDepartment of Medicine, Division of Cardiology Northwestern Memorial Hospital Chicago IL USA.ORCID 0000-0002-2613-2541
Rhonda M Cooper-DeHoffDepartment of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, College of Pharmacy University of Florida Gainesville FL USA.ORCID 0000-0002-5198-130X
Carl J PepineDivision of Cardiovascular Medicine, Department of Medicine University of Florida Gainesville FL USA.ORCID 0000-0002-6011-681X
Michael G FradleyCardio-Oncology Center of Excellence, Perelman School of Medicine University of Pennsylvania Philadelphia PA USA.ORCID 0000-0001-8352-8975
Yan GongDepartment of Pharmacotherapy and Translational Research and Center for Pharmacogenomics and Precision Medicine, College of Pharmacy University of Florida Gainesville FL USA.ORCID 0000-0002-8218-1620
University of Florida · USUniversity of Florida Health · USAugusta University · USNorthwestern Memorial Hospital · USUniversity of Pennsylvania · US

Funding

Using social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2M
Pharmacokinetics of Anti-tuberculosis and Antiretroviral Drugs in ChildrenR01HD071779 · NICHD · UNIVERSITY OF FLORIDA · PI KWARA, AWEWURA JACOB · 2012 to 2022
$6.0M
Preemptive pharmacogenetic testing in medically underserved populationsR01HG011800 · NHGRI · UNIVERSITY OF FLORIDA · PI Julio David Duarte · 2021 to 2026
$3.9M
Training Program for Applied Research and Development in Genomic MedicineT32HG008958 · NHGRI · UNIVERSITY OF FLORIDA · PI Larisa Humma Cavallari, Stephen E. Kimmel · 2018 to 2026
$3.8M
Precision antiplatelet therapy after percutaneous coronary interventionR01HL149752 · NHLBI · UNIVERSITY OF FLORIDA · PI CAVALLARI, LARISA HUMMA, LEE, CRAIG R · 2020 to 2024
$3.5M
NCATS NIH HHS UL1 TR001427NHGRI NIH HHS R01 HG011800NHGRI NIH HHS T32 HG008958NHLBI NIH HHS R01 HL149752NICHD NIH HHS R01 HD071779
6 · The paper itself

Abstract

Background Anthracyclines remain a key treatment for many malignancies but can increase the risk of heart failure or cardiomyopathy. Specific guidelines recommend echocardiography and serum cardiac biomarkers such as BNP (B-type natriuretic peptide) or NT-proBNP (N-terminal proBNP) evaluation before and 6 to 12 months after treatment. Our objective was to evaluate associations between racial and ethnic groups in cardiac surveillance of survivors of cancer after exposure to anthracyclines. Methods and Results Adult patients in the OneFlorida Consortium without prior cardiovascular disease who received at least 2 cycles of anthracyclines were included in the analysis. Multivariable logistic regression was performed to estimate the odds ratios (ORs) and 95% CIs for receiving cardiac surveillance at baseline before anthracycline therapy, 6 months after, and 12 months after anthracycline exposure among different racial and ethnic groups. Among the entire cohort of 5430 patients, 63.4% had a baseline echocardiogram, with 22.3% receiving an echocardiogram at 6 months and 25% at 12 months. Non-Hispanic Black (NHB) patients had a lower likelihood of receiving a baseline echocardiogram than Non-Hispanic White (NHW) patients (OR, 0.75 [95% CI, 0.63-0.88];

Indexed as

CardiomyopathiesNeoplasmsAdultAnthracyclinesAntibiotics, AntineoplasticBiomarkersHeartHumansAnthracyclinesAntibiotics, AntineoplasticBiomarkersanthracyclineshealth disparitiessurveillance

Identifiers

PMID37158063
PMCPMC10227284
OpenAlexW4375955711

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.