ArticleClinical endoscopy2023
Endoscopic vacuum therapy for treatment of spontaneous and iatrogenic upper gastrointestinal defects.
Article in Clinical endoscopy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Endoscopic vacuum therapy for a refractory sigmoid fistula.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2026Article
- Simultaneous Endoluminal Wound Vacuum and Stent Therapy for Large Esophageal Leaks After Esophagectomy.Annals of thoracic surgery short reports · 2026Article
- Endoluminal vacuum therapy for upper gastrointestinal leaks: safe, effective and minimally invasive - insights from a retrospective observational study.Surgical endoscopy · 2026Observational
- Endoscopic vacuum therapy for gastrointestinal transmural defects: a literature review.Clinical endoscopy · 2025Review
- Endoscopic Vacuum Therapy of Upper Gastrointestinal Anastomotic Leaks: How to Deal with the Challenges (with Video).Life (Basel, Switzerland) · 2023Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsEndoscopic vacuum therapy (EVT) can heal a variety of defects within the gastrointestinal (GI) tract via applying negative pressure, which reduces the defect size, aspirates the infected fluid, and promotes granulation tissue. Here we present our experience with EVT as it relates to both spontaneous and iatrogenic upper GI tract perforations, leaks, and fistulas.
methodsThis retrospective study was conducted at four large hospital centers. All patients who underwent EVT between June 2018 and March 2021 were included. Data on multiple variables were collected, including demographics, defect size and location, number and intervals of EVT exchanges, technical success, and hospital length of stay. Student t-test and the chi-squared test were used to analyze the data.
resultsTwenty patients underwent EVT. The most common defect cause was spontaneous esophageal perforation (50%). The most common defect location was the distal esophagus (55%). The success rate was 80%. Seven patients were treated with EVT as the primary closure method. The mean number of exchanges was five with a mean interval of 4.3 days between exchanges. The mean length of hospital stay was 55.8 days.
conclusionEVT is a safe and effective initial management option for esophageal leaks and perforations.
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