Evidence map›Paper›PMID 37157840›Full record

ArticleeLife2023

Human endogenous oxytocin and its neural correlates show adaptive responses to social touch based on recent social context.

Linda Handlin, Giovanni Novembre, Helene Lindholm, Robin Kämpe, Elisabeth Paul, India Morrison

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 21 citations in OpenAlex.

  1. Endocannabinoid contributions to the perception of socially relevant, affective touch in humans.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
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  10. Neuropeptidergic systems in psychiatric disorders.Frontiers in endocrinology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Linda Handlin *Department of Biomedicine, School of Health Sciences, University of Skövde, Skövde, Sweden.
Giovanni Novembre *Division of Neurobiology, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Helene LindholmDepartment of Biomedicine, School of Health Sciences, University of Skövde, Skövde, Sweden.ORCID 0000-0003-2462-0178
Robin KämpeCenter for Medical Image Science and Visualization (CMIV) Linköping University Hospital, Linköping, Sweden.
Elisabeth PaulCenter for Medical Image Science and Visualization (CMIV) Linköping University Hospital, Linköping, Sweden.ORCID 0000-0002-0201-273X
India MorrisonDivision of Neurobiology, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.ORCID 0000-0002-7992-0306
Linköping University · SEUniversity of Skövde · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Both oxytocin (OT) and touch are key mediators of social attachment. In rodents, tactile stimulation elicits the endogenous release of OT, potentially facilitating attachment and other forms of prosocial behavior, yet the relationship between endogenous OT and neural modulation remains unexplored in humans. Using a serial sampling of plasma hormone levels during functional neuroimaging across two successive social interactions, we show that contextual circumstances of social touch influence not only current hormonal and brain responses but also

Indexed as

OxytocinTouch PerceptionBrainFemaleHumansMaleSocial BehaviorSocial EnvironmentTouchOxytocinfMRIhumanneuroscienceoxytocintouch

Identifiers

PMID37157840
PMCPMC10168694
OpenAlexW4367625853

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.