Evidence map›Paper›PMID 37157814›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2023

High-physiological and supra-physiological 1,2-

Matthew G Stovell, Duncan J Howe, Eric P Thelin, Ibrahim Jalloh, Adel Helmy, Mathew R Guilfoyle, Peter Grice, Andrew Mason, Susan Giorgi-Coll, Clare N Gallagher and 5 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Observational
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 3 countries.

Matthew G StovellDivision of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.ORCID 0000-0002-4172-4617
Duncan J HoweDepartment of Chemistry, University of Cambridge, Cambridge, UK.
Eric P ThelinDivision of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
Ibrahim JallohDivision of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
Adel HelmyDivision of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.ORCID 0000-0002-0531-0556
Mathew R GuilfoyleDivision of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
Peter GriceDepartment of Chemistry, University of Cambridge, Cambridge, UK.
Andrew MasonDepartment of Chemistry, University of Cambridge, Cambridge, UK.ORCID 0009-0006-6267-5769
Susan Giorgi-CollDivision of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
Clare N GallagherDivision of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.ORCID 0000-0001-5459-2476
Michael P MurphyMRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK.
David K MenonDivision of Anaesthesia, Department of Medicine, University of Cambridge, Cambridge, UK.
T Adrian CarpenterWolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
Peter J HutchinsonDivision of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
Keri Lh CarpenterDivision of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
University of Cambridge · GBKarolinska University Hospital · SEUniversity of Calgary · CAUniversity of Liverpool · GB

Funding

Department of Health II-C5-0715-20005Department of Health NIHR200986Medical Research Council G0600986Medical Research Council G0600986 ID79068Medical Research Council G0802251Medical Research Council G1002277Medical Research Council G1002277 ID98489Medical Research Council MC_UU_00028/4Wellcome TrustWellcome Trust 220257/Z/20/Z
6 · The paper itself

Abstract

How to optimise glucose metabolism in the traumatised human brain remains unclear, including whether injured brain can metabolise additional glucose when supplied. We studied the effect of microdialysis-delivered 1,2-

Indexed as

GlucoseGlutamineBrainDietary SupplementsHumansLactic AcidMicrodialysisPyruvic AcidGlucoseGlutamineLactic AcidPyruvic Acid1,2-13C2 glucoseBrain metabolismmicrodialysisNMRtraumatic brain injury (human)

Identifiers

PMID37157814
PMCPMC10581237
OpenAlexW4375951560

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.