ReviewAmerican journal of clinical dermatology2023
Acute Generalized Exanthematous Pustulosis: Clinical Features, Differential Diagnosis, and Management.
Review in American journal of clinical dermatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
43 citing papers in PubMed, 73 citations in OpenAlex.
- Clinical Practice Recommendations for Non-Dermatologists on the Diagnostic Suspicion of GPP.Journal of clinical medicine · 2026Review
- Pustules in Stevens-Johnson Syndrome.The American journal of case reports · 2026Article
- Hydroxychloroquine-Induced AGEP with Positive Rechallenge: A Case Report and Mini Review of the Literature.Dermatopathology (Basel, Switzerland) · 2026Article
- Article
- The Role of Genetic Testing in the Differential Diagnosis of Pustular Dermatoses: A Pediatric Case of Generalized Pustular Psoriasis Associated with the IL36RN Variant.Journal of clinical medicine · 2026Article
- Concurrent Drug-induced Rowell Syndrome and Acute Generalized Exanthematous Pustulosis.Acta dermato-venereologica · 2026Article
- A 69-year-old man with acute generalized exanthematous pustulosis.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026Article
- Article
- Kawasaki Disease Accompanied by Acute Generalized Exanthematous Pustulosis.Clinical case reports · 2026Article
- Article
- Acute Generalized Exanthematous Pustulosis: An Integrated Study of 503 Cases with Emphasis on Drug Culprits, Clinical Features, Diagnosis and Treatment.Journal of inflammation research · 2026Article
- Effectiveness and Safety of Spesolimab in Adolescents and Adults with Generalized Pustular Psoriasis.Pragmatic and observational research · 2026Article
- Case Report: Successful treatment of pediatric patients with acute generalized pustular psoriasis with secukinumab.Frontiers in medicine · 2026Article
- HLA allele profiling and association in Thai patients with confirmed beta-lactam hypersensitivity: an NGS-based analysis.Frontiers in pharmacology · 2026Article
- Ampicillin-induced Acute Generalized Exanthematous Pustulosis in a Neonate: A Rare Cutaneous Adverse Reaction.Acta dermato-venereologica · 2025Article
- Combination testing confirming clindamycin induced acute generalized exanthematous pustulosis.JAAD case reports · 2025Article
- Article
- TSC22 domain family member 3 links natural killer cells to CD8+ T cell-mediated drug hypersensitivity.Signal transduction and targeted therapy · 2025Article
- Epidemiology of generalized pustular psoriasis in Germany: Analyzing factors influencing prevalence estimates health insurance data.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025Article
- Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute generalized exanthematous pustulosis (AGEP) is a rare, acute, severe cutaneous adverse reaction mainly attributed to drugs, although other triggers, including infections, vaccinations, ingestion of various substances, and spider bites, have also been described. AGEP is characterized by the development of edema and erythema followed by the eruption of multiple punctate, non-follicular, sterile pustules and subsequent desquamation. AGEP typically has a rapid onset and prompt resolution within a few weeks. The differential diagnoses for AGEP are broad and include infectious, inflammatory, and drug-induced etiologies. Diagnosis of AGEP depends on both clinical and histologic criteria, as cases of overlap with other disease processes have been reported. Management includes removal of the offending drug or treatment of the underlying cause, if necessary, and supportive care, as AGEP is a self-limited disease. This review aims to provide an overview and update on the epidemiology, pathogenesis, reported precipitating factors, differentials, diagnosis, and management of AGEP.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.