Evidence map›Paper›PMID 37156980›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2023

Multiple cranial neuropathy due to varicella zoster virus reactivation without vesicular rash: a challenging diagnosis.

Antonio Stornaiuolo, Rosa Iodice, Roberto De Simone, Cinzia Russo, Marica Rubino, Simone Braca, Angelo Miele, Stefano Tozza, Maria Nolano, Fiore Manganelli

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PubMed Full text at PMC Publisher
In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Antonio StornaiuoloDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University Federico II of Naples, 80131, Naples, Italy. antoniostorna88@gmail.com.ORCID http://orcid.org/0009-0008-2490-2099
Rosa IodiceDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University Federico II of Naples, 80131, Naples, Italy.
Roberto De SimoneDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University Federico II of Naples, 80131, Naples, Italy.
Cinzia RussoDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University Federico II of Naples, 80131, Naples, Italy.
Marica RubinoDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University Federico II of Naples, 80131, Naples, Italy.
Simone BracaDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University Federico II of Naples, 80131, Naples, Italy.
Angelo MieleDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University Federico II of Naples, 80131, Naples, Italy.
Stefano TozzaDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University Federico II of Naples, 80131, Naples, Italy.
Maria NolanoDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University Federico II of Naples, 80131, Naples, Italy.
Fiore ManganelliDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University Federico II of Naples, 80131, Naples, Italy.
University of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ramsay Hunt syndrome is due to reactivation of varicella zoster virus (VZV) dormant in the geniculate ganglion of the facial nerve. The diagnosis is typically based on clinical triad of ipsilateral facial paralysis, otalgia, and vesicles in the auditory canal or the auricle. However, Ramsay Hunt syndrome may occur without skin eruption in up to one third of patients. Moreover, the involvement of other cranial nerves in addition to the facial nerve has been also reported. Herein, we reported a case report of a man who developed a multiple cranial neuropathy caused by VZV reactivation without skin vesicular eruption. The present case underlines a possible diagnostic challenge that clinicians may hit when facing a common disorder such as peripheral facial palsy. Indeed, clinicians must be aware that Ramsay Hunt syndrome may develop without skin vesicular eruption as well it may be complicated by multiple cranial nerve involvement. Antiviral therapy is effective in VZV reactivation for recovery of nerve function.

Indexed as

ExanthemaFacial ParalysisHerpes ZosterHerpes Zoster OticusHerpesvirus 3, HumanHumansMaleSkinCranial neuropathyRamsay Hunt syndromeSine herpeteVZVZoster oticus

Identifiers

PMID37156980
PMCPMC10495477
OpenAlexW4375955594

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.