Evidence map›Paper›PMID 37156900›Full record

ArticleCardiovascular engineering and technology2023

Optimization of 4D Flow MRI Spatial and Temporal Resolution for Examining Complex Hemodynamics in the Carotid Artery Bifurcation.

Retta El Sayed, Alireza Sharifi, Charlie C Park, Diogo C Haussen, Jason W Allen, John N Oshinski

Open access · greenAbstract read
In one paragraph

Article in Cardiovascular engineering and technology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Retta El SayedDepartment of Biomedical Engineering, The Wallace H. Coulter, Emory University and Georgia Institute of Technology, Atlanta, GA, USA.ORCID 0000-0002-0282-8333
Alireza SharifiDepartment of Radiology & Imaging Sciences, Emory University, 1364 Clifton Rd, Atlanta, GA, 30322, USA.
Charlie C ParkDepartment of Radiology & Imaging Sciences, Emory University, 1364 Clifton Rd, Atlanta, GA, 30322, USA.
Diogo C HaussenDepartment of Neurology, Emory University, Atlanta, GA, USA.
Jason W AllenDepartment of Biomedical Engineering, The Wallace H. Coulter, Emory University and Georgia Institute of Technology, Atlanta, GA, USA.
John N OshinskiDepartment of Biomedical Engineering, The Wallace H. Coulter, Emory University and Georgia Institute of Technology, Atlanta, GA, USA. jnoshin@emory.edu.ORCID 0000-0003-0043-7870
Emory University · USGeorgia Institute of Technology · USEmory Healthcare · US

Funding

Coronary Fractional Flow Reserve Determined Using MRI and CFDR01EB027774 · NIBIB · EMORY UNIVERSITY · PI OSHINSKI, JOHN N · 2020 to 2025
$1.7M
Hemodynamics, thrombosis, and stroke risk in patients with carotid websR21NS114603 · NINDS · EMORY UNIVERSITY · PI ALLEN, JASON WILLIAM, OSHINSKI, JOHN N · 2020 to 2020
$429k
NIBIB NIH HHS R01 EB027774NINDS NIH HHS R21 NS114603
6 · The paper itself

Abstract

backgroundThree-dimensional, ECG-gated, time-resolved, three-directional, velocity-encoded phase-contrast MRI (4D flow MRI) has been applied extensively to measure blood velocity in great vessels but has been much less used in diseased carotid arteries. Carotid artery webs (CaW) are non-inflammatory intraluminal shelf-like projections into the internal carotid artery (ICA) bulb that are associated with complex flow and cryptogenic stroke. PURPOSE: Optimize 4D flow MRI for measuring the velocity field of complex flow in the carotid artery bifurcation model that contains a CaW.

methodsA 3D printed phantom model created from computed tomography angiography (CTA) of a subject with CaW was placed in a pulsatile flow loop within the MRI scanner. 4D Flow MRI images of the phantom were acquired with five different spatial resolutions (0.50-2.00  mm HYPOTHESIS: An optimized 4D flow MRI protocol will provide a good correlation with CFD velocity and TAWSS values in areas of complex flow within a clinically feasible scan time (~ 10 min).

resultsSpatial resolution affected the velocity values, time average flow, and TAWSS measurements. Qualitatively, a spatial resolution of 0.50  mm

conclusionA spatial resolution of 0.74-1.00  mm

Indexed as

HemodynamicsMagnetic Resonance ImagingBlood Flow VelocityCarotid ArteriesPulsatile FlowStress, Mechanical4D flow MRICarotid webPhantom modelSpatial resolutionTemporal resolution

Identifiers

PMID37156900
PMCPMC10524741
OpenAlexW4375860763

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.