Evidence map›Paper›PMID 37156424›Full record

Trial reportJournal of substance use and addiction treatment2023

Pilot randomized controlled trial of a hospital-based substance use treatment and recovery team (START) to improve initiation of medication for alcohol or opioid use disorder and linkage to follow-up care.

Allison J Ober, Karen C Osilla, David J Klein, Lane F Burgette, Isabel Leamon, Mia W Mazer, Gabrielle Messineo, Stacy Collier, Samuel Korouri, Katherine E Watkins and 3 more

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of substance use and addiction treatment, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Allison J OberRAND Corporation, Santa Monica, CA, United States of America. Electronic address: ober@rand.org.
Karen C OsillaStanford University School of Medicine, Palo Alto, CA, United States of America.
David J KleinRAND Corporation, Santa Monica, CA, United States of America.
Lane F BurgetteRAND Corporation, Santa Monica, CA, United States of America.
Isabel LeamonRAND Corporation, Santa Monica, CA, United States of America.
Mia W MazerCedars-Sinai Medical Center, Los Angeles, CA, United States of America.
Gabrielle MessineoCedars-Sinai Medical Center, Los Angeles, CA, United States of America.
Stacy CollierCedars-Sinai Medical Center, Los Angeles, CA, United States of America.
Samuel KorouriCedars-Sinai Medical Center, Los Angeles, CA, United States of America.
Katherine E WatkinsRAND Corporation, Santa Monica, CA, United States of America.
Waguih IshakCedars-Sinai Medical Center, Los Angeles, CA, United States of America.
Teryl NuckolsCedars-Sinai Medical Center, Los Angeles, CA, United States of America.
Itai DanovitchCedars-Sinai Medical Center, Los Angeles, CA, United States of America.
Cedars-Sinai Medical Center · USRAND Corporation · USPalo Alto University · US

Funding

Pilot Test of a Collaborative Care Team for Medical Inpatients with Opioid and Alcohol Use DisordersR34DA047492 · NIDA · RAND CORPORATION · PI DANOVITCH, ITAI, OBER, ALLISON · 2019 to 2021
$822k
NIDA NIH HHS R34 DA047492
6 · The paper itself

Abstract

objectivesWe conducted a pilot randomized controlled trial (RCT) to explore whether a hospital inpatient addiction consult team (Substance Use Treatment and Recovery Team [START]) based on collaborative care was feasible, acceptable to patients, and whether it could improve uptake of medication in the hospital and linkage to care after discharge, as well as reduce substance use and hospital readmission. The START consisted of an addiction medicine specialist and care manager who implemented a motivational and discharge planning intervention.

methodsWe randomized inpatients age ≥ 18 with a probable alcohol or opioid use disorder to receive START or usual care. We assessed feasibility and acceptability of START and the RCT, and we conducted an intent-to-treat analysis on data from the electronic medical record and patient interviews at baseline and 1-month postdischarge. The study compared RCT outcomes (medication for alcohol or opioid use disorder, linkage to follow-up care after discharge, substance use, hospital readmission) between arms by fitting logistic and linear regression models.

findingsOf 38 START patients, 97 % met with the addiction medicine specialist and care manager; 89 % received ≥8 of 10 intervention components. All patients receiving START found it to be somewhat or very acceptable. START patients had higher odds of initiating medication during the inpatient stay (OR 6.26, 95 % CI = 2.38-16.48, p < .001) and being linked to follow-up care (OR 5.76, 95 % CI = 1.86-17.86, p < .01) compared to usual care patients (N = 50). The study found no significant differences between groups in drinking or opioid use; patients in both groups reported using fewer substances at the 1-month follow-up.

conclusionsPilot data suggest START and RCT implementation are feasible and acceptable and that START may facilitate medication initiation and linkage to follow-up for inpatients with an alcohol or opioid use disorder. A larger trial should assess effectiveness, covariates, and moderators of intervention effects.

Indexed as

Behavior, AddictiveOpioid-Related DisordersAftercareEthanolHospitalsHumansPilot ProjectsEthanolAddiction consult teamCollaborative careInpatientLinkage to follow-upMedications for opioid use disorder (MOUD)Opioid use disorder (OUD)

Identifiers

PMID37156424
PMCPMC10330512
OpenAlexW4372342988

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.