ArticleThe Journal of thoracic and cardiovascular surgery2024
Limited cumulative experience with ex vivo lung perfusion is associated with inferior outcomes after lung transplantation.
Article in The Journal of thoracic and cardiovascular surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 20 citations in OpenAlex.
- Impact of ex vivo lung perfusion evaluation on donation after circulatory death in lung transplantation.JTCVS techniques · 2026Article
- Lung transplantation from donation after circulatory death donors over 55 years old: A national analysis of outcomes and utilization.JHLT open · 2026Article
- Time as a Therapeutic Ally: The Promise of Long-Term Solid Organ and Tissue Perfusion.Transplant international : official journal of the European Society for Organ Transplantation · 2026Review
- Comparative evaluation of single-artery cannulation with passive venous drainage versus traditional dual-cannula ex vivo lung perfusion in a rat model.Animal models and experimental medicine · 2026Article
- Thoracoabdominal Normothermic Regional Perfusion and Donation After Circulatory Death Lung Use.JAMA network open · 2025Article
- Impact of Ex Vivo Lung Perfusion on Inpatient Cost: A Propensity Score-Matched Analysis of the US Nationwide Healthcare Cost and Utilization Project Database.Clinical transplantation · 2025Article
- Review
- Disparities in lung transplantation in children.Pediatric pulmonology · 2024Review
- Pushing the Survival Bar Higher: Two Decades of Innovation in Lung Transplantation.Journal of clinical medicine · 2024Review
- A Split-LungTransplant international : official journal of the European Society for Organ Transplantation · 2024Article
- Epidemiology and Long-Term Outcomes in Thoracic Transplantation.Journal of cardiovascular development and disease · 2023Review
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveEx vivo lung perfusion (EVLP) allows for prolonged preservation and evaluation/resuscitation of donor lungs. We evaluated the influence of center experience with EVLP on lung transplant outcomes.
methodsWe identified 9708 isolated, first-time adult lung transplants from the United Network for Organ Sharing database (March 1, 2018-March 1, 2022), 553 (5.7%) involved using donor lungs after EVLP. Using the total volume of EVLP lung transplants per center during the study period, centers were dichotomized into low- (1-15 cases) and high-volume (>15 cases) EVLP centers.
resultsForty-one centers performed EVLP lung transplants, including 26 low-volume and 15 high-volume centers (median volume, 3 vs 23 cases; P < .001). Recipients at low-volume centers (n = 109) had similar baseline comorbidities compared with high-volume centers (n = 444). Low-volume centers used numerically more donation after circulatory death donors (37.6 vs 28.4%; P = .06) and more donors with Pao
conclusionsThe use of EVLP in lung transplantation remains limited. Increasing cumulative EVLP experience is associated with improved outcomes of lung transplantation using EVLP-perfused allografts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.