Evidence map›Paper›PMID 37155965›Full record

ReviewJournal of experimental botany2023

Synthetic developmental biology: molecular tools to re-design plant shoots and roots.

Elif Gediz Kocaoglan, Dhanya Radhakrishnan, Naomi Nakayama

Abstract readReview
In one paragraph

Review in Journal of experimental botany, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. The Promise of Synthetic Biology for Redesigning Plant Architecture.International journal of molecular sciences · 2026
    Review
  2. From Structure to Function of Promoters and 5'UTRs in Maize.International journal of molecular sciences · 2026
    Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elif Gediz KocaoglanDepartment of Bioengineering, Centre for Synthetic Biology, Imperial College London, London SW7 2AZ, UK.
Dhanya RadhakrishnanDepartment of Bioengineering, Centre for Synthetic Biology, Imperial College London, London SW7 2AZ, UK.
Naomi NakayamaDepartment of Bioengineering, Centre for Synthetic Biology, Imperial College London, London SW7 2AZ, UK.ORCID 0000-0002-9390-3545

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plant morphology and anatomy strongly influence agricultural yield. Crop domestication has strived for desirable growth and developmental traits, such as larger and more fruits and semi-dwarf architecture. Genetic engineering has accelerated rational, purpose-driven engineering of plant development, but it can be unpredictable. Developmental pathways are complex and riddled with environmental and hormonal inputs, as well as feedback and feedforward interactions, which occur at specific times and places in a growing multicellular organism. Rational modification of plant development would probably benefit from precision engineering based on synthetic biology approaches. This review outlines recently developed synthetic biology technologies for plant systems and highlights their potential for engineering plant growth and development. Streamlined and high-capacity genetic construction methods (Golden Gate DNA Assembly frameworks and toolkits) allow fast and variation-series cloning of multigene transgene constructs. This, together with a suite of gene regulation tools (e.g. cell type-specific promoters, logic gates, and multiplex regulation systems), is starting to enable developmental pathway engineering with predictable outcomes in model plant and crop species.

Indexed as

Genetic EngineeringSynthetic BiologyCloning, MolecularDevelopmental BiologyDNAPlantsDNAGrowth and developmentPhytobricksplant synthetic biologyprecision breedingsynthetic developmental biologysynthetic morphology

Identifiers

PMID37155965
PMCPMC10826796

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.