Evidence map›Paper›PMID 37155911›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

The DedA superfamily member PetA is required for the transbilayer distribution of phosphatidylethanolamine in bacterial membranes.

Ian J Roney, David Z Rudner

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
12.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 31 citations in OpenAlex.

  1. The phenotypic landscape of the model firmicuteProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. ThemBio · 2026
    Article
  3. Control of theJournal of bacteriology · 2025
    Article
  4. Article
  5. Article
  6. MprF fromScience advances · 2025
    Article
  7. PgpP is a broadly conserved phosphatase required for phosphatidylglycerol lipid synthesis.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Lipid Trafficking in Diverse Bacteria.Accounts of chemical research · 2025
    Review
  9. Article
  10. Lipopeptide antibiotics disrupt interactions of undecaprenyl phosphate with UptA.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  11. Review
  12. Microbiology spectrum · 2024
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ian J RoneyDepartment of Microbiology, Harvard Medical School, Boston, MA 02115.ORCID 0000-0002-3320-1170
David Z RudnerDepartment of Microbiology, Harvard Medical School, Boston, MA 02115.
Harvard University · US

Funding

Targeting bacterial cell wall biogenesis for the development of novel antimicrobU19AI109764 · NIAID · HARVARD MEDICAL SCHOOL · PI KASPER, DENNIS L. · 2014 to 2018
$25.2M
Project 3: Defining and defeating the mechanisms of outer membrane biogenesis in Gram-negative bacteriaU19AI158028 · NIAID · HARVARD MEDICAL SCHOOL · PI WALKER, SUZANNE · 2022 to 2025
$10.1M
Growth and differentiation in Bacillus subtilisR35GM145299 · NIGMS · HARVARD MEDICAL SCHOOL · PI DAVID Z RUDNER · 2022 to 2026
$2.9M
NIAID NIH HHS U19 AI109764NIAID NIH HHS U19 AI158028NIGMS NIH HHS R35 GM145299
6 · The paper itself

Abstract

The sorting of phospholipids between the inner and outer leaflets of the membrane bilayer is a fundamental problem in all organisms. Despite years of investigation, most of the enzymes that catalyze phospholipid reorientation in bacteria remain unknown. Studies from almost half a century ago in

Indexed as

PhosphatidylethanolaminesPhospholipidsBacteriaCell MembraneMembrane Transport ProteinsMembrane Transport ProteinsPhosphatidylethanolaminesPhospholipidsDedAflippaselipid transportmembrane biogenesisphosphatidylethanolamine

Identifiers

PMID37155911
PMCPMC10193950
OpenAlexW4375955896

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.