Evidence map›Paper›PMID 37155907›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

G-quadruplexes rescuing protein folding.

Ahyun Son, Veronica Huizar Cabral, Zijue Huang, Theodore J Litberg, Scott Horowitz

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
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  7. Review
  8. Contributions of Folded and Disordered Domains to RNA Binding by HNRNPR.bioRxiv : the preprint server for biology · 2025
    Article
  9. G-quadruplexes and their unexpected ability to fold proteins.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Article
  11. Article
  12. G-quadruplexes catalyze protein folding by reshaping the energetic landscape.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  13. Chronic RNA G-quadruplex Accumulation in Aging and Alzheimer's Disease.bioRxiv : the preprint server for biology · 2025
    Article
  14. Review
  15. Article
  16. Article
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  18. Review
  19. Article
  20. An intein-based biosensor to measure protein stability in vivo.Protein science : a publication of the Protein Society · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ahyun SonDepartment of Chemistry & Biochemistry, Knoebel Institute for Healthy Aging, University of Denver, Denver, CO 80208.ORCID 0000-0002-7979-0409
Veronica Huizar CabralDepartment of Chemistry & Biochemistry, Knoebel Institute for Healthy Aging, University of Denver, Denver, CO 80208.
Zijue HuangDepartment of Chemistry & Biochemistry, Knoebel Institute for Healthy Aging, University of Denver, Denver, CO 80208.ORCID 0000-0002-4870-6083
Theodore J LitbergDepartment of Chemistry & Biochemistry, Knoebel Institute for Healthy Aging, University of Denver, Denver, CO 80208.ORCID 0000-0001-5353-8451
Scott HorowitzDepartment of Chemistry & Biochemistry, Knoebel Institute for Healthy Aging, University of Denver, Denver, CO 80208.ORCID 0000-0002-1148-0105
University of Denver · US

Funding

Nucleic Acids Roles in Protein Folding and AggregationR35GM142442 · NIGMS · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI Scott Andrew Horowitz · 2021 to 2026
$2.4M
NIGMS NIH HHS R35 GM142442
6 · The paper itself

Abstract

Maintaining the health of the proteome is a critical cellular task. Recently, we found G-quadruplex (G4) nucleic acids are especially potent at preventing protein aggregation in vitro and could at least indirectly improve the protein folding environment of

Indexed as

G-QuadruplexesNucleic AcidsEscherichia coliProtein AggregatesProtein FoldingNucleic AcidsProtein AggregatesG4protein foldingproteostasisquadruplex

Identifiers

PMID37155907
PMCPMC10194009
OpenAlexW4375956202

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.