Evidence map›Paper›PMID 37155872›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

CDYL reinforces male gonadal sex determination through epigenetically repressing

Naoki Okashita, Ryo Maeda, Makoto Tachibana

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Overexpression ofZoological research · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Naoki OkashitaLaboratory of Epigenome Dynamics, Graduate School of Frontier Biosciences, Osaka University, Suita, Osaka 565-0871, Japan.ORCID 0000-0003-1795-2115
Ryo MaedaLaboratory of Epigenome Dynamics, Graduate School of Frontier Biosciences, Osaka University, Suita, Osaka 565-0871, Japan.ORCID 0000-0003-3302-7392
Makoto TachibanaLaboratory of Epigenome Dynamics, Graduate School of Frontier Biosciences, Osaka University, Suita, Osaka 565-0871, Japan.ORCID 0000-0001-7977-1120
The University of Osaka · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In mammals, male and female gonads initially develop from bipotential progenitor cells, which can differentiate into either testicular or ovarian cells. The decision to adopt a testicular or ovarian fate relies on robust genetic forces, i.e., activation of the testis-determining gene

Indexed as

Epigenesis, GeneticSex Determination ProcessesAnimalsCo-Repressor ProteinsFemaleGene Expression Regulation, DevelopmentalGonadsHydro-LyasesMaleMammalsMiceOvarySex-Determining Region Y ProteinSOX9 Transcription FactorTestisWnt4 ProteinCdyl protein, mouseCo-Repressor ProteinsHydro-LyasesSex-Determining Region Y ProteinSOX9 Transcription FactorWnt4 ProteinWnt4 protein, mouseCDYLgonadal sex determinationH3K27me3WNT4

Identifiers

PMID37155872
PMCPMC10193937
OpenAlexW4375955741

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.