Evidence map›Paper›PMID 37155841›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Antithetic effects of agonists and antagonists on the structural fluctuations of TRPV1 channel.

Ayumi Sumino, Yimeng Zhao, Daichi Mukai, Takashi Sumikama, Leonardo Puppulin, Motoyuki Hattori, Mikihiro Shibata

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. A journey from molecule to physiology andFrontiers in pharmacology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Ayumi SuminoWorld Premier International Research Center Initiative, Nano Life Science Institute, Kanazawa University, Kanazawa 920-1192, Japan.ORCID 0000-0001-9385-0431
Yimeng ZhaoState Key Laboratory of Genetic Engineering, Collaborative Innovation Center of Genetics and Development, Shanghai Key Laboratory of Bioactive Small Molecules, Department of Physiology and Neurobiology, School of Life Sciences, Fudan University, Shanghai 200438, China.ORCID 0000-0002-8913-3568
Daichi MukaiDivision of Nano Life Science, Graduate School of Frontier Science Initiative, Kanazawa University, Kanazawa 920-1192, Japan.
Takashi SumikamaWorld Premier International Research Center Initiative, Nano Life Science Institute, Kanazawa University, Kanazawa 920-1192, Japan.ORCID 0000-0003-3696-5720
Leonardo PuppulinWorld Premier International Research Center Initiative, Nano Life Science Institute, Kanazawa University, Kanazawa 920-1192, Japan.
Motoyuki HattoriState Key Laboratory of Genetic Engineering, Collaborative Innovation Center of Genetics and Development, Shanghai Key Laboratory of Bioactive Small Molecules, Department of Physiology and Neurobiology, School of Life Sciences, Fudan University, Shanghai 200438, China.ORCID 0000-0002-5327-5337
Mikihiro ShibataWorld Premier International Research Center Initiative, Nano Life Science Institute, Kanazawa University, Kanazawa 920-1192, Japan.ORCID 0000-0001-5041-3979
Kanazawa University · JPFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transient receptor potential vanilloid member 1 (TRPV1) is a heat and capsaicin receptor that allows cations to permeate and cause pain. As the molecular basis for temperature sensing, the heat capacity (Δ

Indexed as

DiterpenesTransient Receptor Potential ChannelsCapsaicinCationsHot TemperatureTRPV Cation ChannelsCapsaicinCationsDiterpenesTransient Receptor Potential ChannelsTRPV Cation Channelscapsazepinefluctuationhigh-speed atomic force microscopyresiniferatoxinTRPV1 channel

Identifiers

PMID37155841
PMCPMC10193963
OpenAlexW4375955763

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.