ArticlePloS one2023
Longitudinal association between handgrip strength, gait speed and risk of serious falls in a community-dwelling older population.
Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical importance of simple muscular fitness tests to predict long-term health conditions: a systematic review and meta-analysis of 94 cohort studies.British journal of sports medicine · 2026Pooled it
- Implementing a patient-oriented pole walking intervention in retirement homes: A non-randomized feasibility trial.PloS one · 2026Trial
- Impact of a functional gait training program as a complementary strategy to improve physical function in older adults: a randomized clinical trial.BMC geriatrics · 2025Trial
- Associations Between Blood Concentrations of Sex Hormones and Physical Function in Community-Dwelling Older Women: A Prospective Cohort Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Trial
- Neural contributions to age-related handgrip weakness revealed by multi-finger force deficit and dual-task testing.GeroScience · 2026Article
- Maximal Handgrip Strength as a Measure of General Functional Capacity Rather than Parkinson's Disease-Specific Impairment.Brain sciences · 2026Article
- Handgrip strength in young recreational skiers: Is it related to the risk of falling?European journal of translational myology · 2026Article
- The role of dominant handgrip strength in fall occurrence possibility and frequency.BMC public health · 2026Article
- Obstructive sleep apnea risk is associated with poor physical performance: a cross-sectional analysis of the U.S. health and retirement study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026Article
- A multidimensional analysis of fall risk among older adults in India: evidence from the longitudinal ageing study in India (LASI).European geriatric medicine · 2026Article
- Machine learning-based prediction model for fall risk among individuals with arthritis in China: an analysis using the China Health and Retirement Longitudinal Study (CHARLS) database.Journal of health, population, and nutrition · 2026Article
- Clinically Meaningful or Just Measurable? What Physiologic Outcomes Tell Us About Aging Interventions.Current geriatrics reports · 2025Article
- Are we giving too much weight to lean mass loss?Molecular metabolism · 2025Review
- Personality and falls: evidence from three samples.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Association Between Physical Performance, Gait Variability, and Fall Risk in Community-Dwelling Older Adults: Predictive Validity of Step-Width Variability for Screening of Fall Risk.Life (Basel, Switzerland) · 2025Article
- Associations Between Physical Activity Frequency, Handgrip Strength, and Limitations in Activities of Daily Living in Middle-Aged and Older Adults with Widespread Pain: A Cross-Sectional Study Using Data from the SHARE Project.Geriatrics (Basel, Switzerland) · 2025Article
- Yearlong Evaluation of Fall Risk Determinants Among 40 Older Adults in Two Residential Assisted Living Facilities.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Vitamin D and Sarcopenia: Implications for Muscle Health.Biomedicines · 2025Review
- What determines gait speed in community-living older adults? A relative weight analysis.European geriatric medicine · 2025Article
- Association between grip strength level and fall experience among older Chinese adults: a cross-sectional study from the CHARLS.BMC geriatrics · 2025Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
objectiveBoth grip strength and gait speed can be used as markers of muscle function, however, no previous study has examined them in the same population with respect to risk of falls.
methodsIn this prospective cohort study, utilising data from the ASPirin in Reducing Events in the Elderly (ASPREE) trial and ASPREE-Fracture substudy, we analysed the association of grip strength and gait speed and serious falls in healthy older adults. Grip strength was measured using a handheld dynamometer and gait speed from 3-metre timed walks. Serious falls were confined to those involving hospital presentation. Cox regression was used to calculate hazard ratios (HR) and 95% confidence intervals (CI) for associations with falls.
resultsOver an average of 4.0±1.3 years, amongst 16,445 participants, 1,533 had at least one serious fall. After adjustment for age, sex, physical activity, body mass index, Short Form 12 (state of health), chronic kidney disease, polypharmacy and aspirin, each standard deviation (SD) lower grip strength was associated with 27% (HR 1.27, 95% CI 1.17-1.38) higher risk of falls. The results remained the same for males and females. There was a dose-response relationship in the association between grip strength and falls risk. The higher risk of falls was observed in males in all body mass index (BMI) categories, but only in obese females. The association between gait speed and falls risk was weaker than the association between grip strength and falls risk.
conclusionsAll males and only obese females with low grip strength appear to be at the greatest risk of serious falls. These findings may assist in early identification of falls.
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