Evidence map›Paper›PMID 37155521›Full record

ArticleResearch in diagnostic and interventional imaging2023

Measurement of renal cortical fibrosis by CT scan.

John D Olson, Janet A Tooze, Daniel J Bourland, J Mark Cline, Eduardo B Faria, Eric P Cohen

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Research in diagnostic and interventional imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

John D OlsonDepartment of Comparative Medicine, Wake Forest University, Winston-Salem, NC, 27101, USA.
Janet A ToozeDepartment of Comparative Medicine, Wake Forest University, Winston-Salem, NC, 27101, USA.
Daniel J BourlandDepartment of Comparative Medicine, Wake Forest University, Winston-Salem, NC, 27101, USA.
J Mark ClineDepartment of Comparative Medicine, Wake Forest University, Winston-Salem, NC, 27101, USA.
Eduardo B FariaDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Eric P CohenNephrology Division, Department of Medicine, New York University Grossman School of Medicine, New York, NY, 10016, USA.
Wake Forest University · USNew York University · USUniversity of Maryland, Baltimore · US

Funding

The Wake Forest Nonhuman Primate Radiation Survivor CohortU01AI150578 · NIAID · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI J. MARK CLINE · 2020 to 2026
$23.7M
NIAID NIH HHS U01 AI150578
6 · The paper itself

Abstract

Rationale and objectives: The accurate, non-invasive, and rapid measurement of renal cortical fibrosis is needed for well-defined benchmarks of permanent injury and for use of anti-fibrotic agents. It is also needed for non-invasive and rapid assessment of the chronicity of human renal diseases. Materials and methods: We have used a non-human primate model of radiation nephropathy to develop a novel method of size-corrected CT imaging to quantify renal cortical fibrosis. Results: Our method has an area under the receiver operating curve of 0.96, which is superior to any other non-invasive method of measuring renal fibrosis. Conclusion: Our method is suitable for immediate translation to human clinical renal diseases.

Indexed as

CT scanNon-human primateRenal cortical fibrosis

Identifiers

PMID37155521
PMCPMC10124964
OpenAlexW4322726660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.