ReviewMolecular biology reports2023
Organophosphate pesticide-induced toxicity through DNA damage and DNA repair mechanisms.
Review in Molecular biology reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 60 citations in OpenAlex.
- Protective effects of pistachio pericarp essential oil against diazinon-induced oxidative stress and follicular damage in the ovaries of NMRI mice.Journal of ovarian research · 2026Article
- Melatonin mitigates dichlorvos-induced derangements in the testes and epididymis of male Wistar rats.Animal reproduction · 2026Article
- The mitigating effects of Tribulus terrestris extract on the cytotoxic, genotoxic, biochemical and phytotoxic effects of omethoate in roots of Allium cepa bulbs.Scientific reports · 2025Article
- Effect of pesticide exposure on systemic inflammatory biomarkers: a meta-analysis, and trial sequential analysis.Journal of environmental health science & engineering · 2025Review
- Low-dose radiation and malathion co-exposure instigates long-term neurological sequelae and synergistic disruption of lipid homeostasis and energy metabolism in the hippocampus.Scientific reports · 2025Article
- The Influence of Blood Titanium Levels on DNA Damage in Brazilian Workers Occupationally Exposed to Different Chemical Agents.Biological trace element research · 2025Article
- Serial Cross-Sectional Human Biomonitoring Analysis of Pesticide Exposure Patterns and Their Association with Lipid Metabolism Biomarkers: The Mediating Role of Liver Function.Environment & health (Washington, D.C.) · 2025Article
- A study investigating the multifaceted toxicity induced by triflumuron insecticide in Allium cepa L.Scientific reports · 2025Article
- Toxicological assessment of omethoate insecticide in Allium cepa L.Scientific reports · 2025Article
- A new quinoline-based fluorescent-colorimetric chemosensor for sensitive and selective "on-off" detection of PbRSC advances · 2025Article
- Follicular DNA Damage and Pesticide Exposure Among Latinx Children in Rural and Urban Communities.Exposure and health · 2024Article
- Mechanisms of Organophosphate Toxicity and the Role of Acetylcholinesterase Inhibition.Toxics · 2023Review
- Polymorphisms in DNA Repair Genes as Biomarkers of Susceptibility for Pesticide-Induced DNA Damage among Agricultural Workers: A Review.Indian journal of occupational and environmental medicineReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Organophosphate pesticides (OPs) are widely used in agriculture, healthcare, and other industries due to their ability to kill pests. However, OPs can also have genotoxic effects on humans who are exposed to them. This review summarizes the research on DNA damage caused by OPs, the mechanisms behind this damage, and the resulting cellular effects. Even at low doses, OPs have been shown to damage DNA and cause cellular dysfunction. Common phenomena seen in cells that are exposed to OPs include the formation of DNA adducts and lesions, single-strand and double-strand DNA breaks, and DNA and protein inter and intra-cross-links. The present review will aid in comprehending the extent of genetic damage and the impact on DNA repair pathways caused by acute or chronic exposure to OPs. Additionally, understanding the mechanisms of the effects of OPs will aid in correlating them with various diseases, including cancer, Alzheimer's, and Parkinson's disease. Overall, knowledge of the potential adverse effects of different OPs will help in monitoring the health complications they may cause.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.