ArticlePediatric nephrology (Berlin, Germany)2023
Liver and kidney ultrasound elastography in children and young adults with hypertension or chronic kidney disease.
Article in Pediatric nephrology (Berlin, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- Ultrasound elastography in pediatric care: bridging innovation and noninvasive diagnostics.Italian journal of pediatrics · 2026Review
- Serum and urinary uromodulin concentration in children and young adults with chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2025Article
- Interleukin-2 Receptor as a Marker of Oxidative Stress in Paediatric Patients with Chronic Kidney Disease or Hypertension.Children (Basel, Switzerland) · 2025Article
- Ultrasound innovations in abdominal radiology: techniques and clinical applications in pediatric imaging.Abdominal radiology (New York) · 2025Review
- Prediction of pulmonary artery sling in children using echocardiography: scoring based on pulmonary artery bifurcation and pulmonary valve ring distance.Cardiovascular ultrasound · 2025Article
- Application of shear wave elastography in the assessment of renal cortical elasticity in patients with hypertension.Frontiers in medicine · 2025Article
- Effect of proteinuria at relapse on shear wave velocity assessed using ultrasound elastography in children with idiopathic nephrotic syndrome.Journal of medical ultrasonics (2001) · 2024Observational
- Obesity and Body Composition in Relation to Liver and Kidney Ultrasound Elastography in Paediatric Patients with Either Hypertension or Chronic Kidney Disease.Children (Basel, Switzerland) · 2023Article
- Ultrasound Elastography in Children.Children (Basel, Switzerland) · 2023Review
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3 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundUltrasound elastography is a research method increasingly used to measure tissue elasticity. The aim of the study was to assess its usability in pediatric patients with either chronic kidney disease (CKD) or hypertension.
methodsA total of 46 patients with CKD (group 1), 50 patients with hypertension (group 2), and 33 healthy participants as the control group were included. In all, we performed studies assessing their cardiovascular risk along with liver and kidney elastography.
resultsLiver elastography parameters were increased compared to those in the control group (1.49 m/s, p = 0.007, in group 1 and 1.52 m/s, p < 0.001, in group 2, vs. 1.41 m/s among controls). Kidney elastography parameters were significantly higher in group 2 (1.9 m/s, p = 0.001, and 1.9 m/s, p = 0.003, in each kidney) when compared to group 1 (1.79 m/s and 1.81 m/s). Additionally, all participants were divided according to overweight/obesity and normal weight status, where both liver (1.53 m/s vs. 1.45 m/s, p < 0.001) and kidney parameters (1.96 m/s and 1.92 m/s vs. 1.81 m/s and 1.84 m/s, p = 0.002) were significantly higher in the group of overweight/obese subjects.
conclusionsUltrasound elastography of the liver and kidney is feasible in pediatric patients with either CKD or hypertension, showing increased liver stiffness parameters in both groups, further aggravated by obesity. In obese patients with CKD, kidney stiffness also increased indicating a negative effect of clustering cardiovascular risk factors leading to decreased kidney elasticity. Further research is warranted. A higher resolution version of the Graphical abstract is available as Supplementary information.
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